Johnsonella ignava

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Johnsonella ignava is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 32%. Johnsonella ignava is probably a rare gut coloniser. (Moore1994a; Willems2011dBergey)



  • This organism has been recovered from gingival crevices of humans with gingivitis and periodontitis. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Moore1994a); (Willems2011dBergey);
    Character Response
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 37℃;
    • SPECIAL FEATURES (Moore1994a); (Willems2011dBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate (trace); lactate (trace); isobutyrate (trace); succinate (trace); isovalerate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Johnsonella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  gingival crevices of humans with gingivitis and periodontitis
    DNA G+C(%):  32
    Mid T(℃):  37(+)
    Bile reaction(%):  20(neg)
    		DNA:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Amygdalin:  neg Glycogen:  neg Starch:  neg Xylan:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg DNAse:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  trace(+) Lactate:  trace(+) Isobutyrate:  trace(+) Succinate:  trace(+) Isovalerate:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR JOHNSONELLA IGNAVA
  • Moore1994a - Oribaculum catoniae gen. nov., sp. nov.: Catonella morbi gen. nov., sp. nov.: Hallella seregens gen. nov., sp. nov.: Johnsonella ignava gen. nov., sp. nov.: and Dialister pneumosintes gen. nov., comb. nov., nom. rev., Anaerobic Gram-Negative Bacilli from the Human Gingival Crevice.
  • Willems1995b - Evidence for the placement of the gram-negative Catonella morbi (Moore and Moore) and Johnsonella ignava (Moore and Moore) within the Clostridium subphylum of the gram-positive bacteria on the basis of 16S rRNA sequences.
  • Willems2011dBergey - Bergey's manual of systematic bacteriology. Vol. 3, The firmicutes. Family Lachnospiraceae, Genus X. Johnsonella
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR JOHNSONELLA IGNAVA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
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    • Added: January 19, 2022