Kerstersia gyiorum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Kerstersia gyiorum is a Gram-negative, non-spore-forming, variably-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 62.7-62.9%. Kerstersia gyiorum is probably a rare gut coloniser. (Coenye2003a)



  • This organism has been recovered from clinical sources (sputum, wound - CCUG) and human faeces (CCUG). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Coenye2003a);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 0.5% salt; tolerates 4.5% salt; doesn't tolerate 6.0% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 28℃; grows at 42℃; Grows optimally at 33-37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • alanine; D-alanine; γ-aminobutyrate; aspartate; glutamate; DL-kynurenine; ornithine; phenylalanine; proline; tyrosine; acetate; butyrate; caprate; caproate; citrate; fumarate; heptanoate; 3-hydroxybutyrate; 4-hydroxybenzoate; DL-lactate; L-malate; nonanoate; phenylacetate; propionate; pyruvate; succinate; valerate; glutamine; 2-aminobenzoate; D-malate;
  • ±
  • Strain-dependent substrate utilisation:
  • cellubiose; gluconate; gentiobiose; glycerol; β-alanine; 2-aminobutyrate; cysteine; isoleucine; leucine; methionine; norleucine; threonine; tryptamine; tryptophan; valine; aconitate; adipate; azelate; caprylate; citraconate; glutarate; isobutyrate; isovalerate; itaconate; 2-ketoglutarate; levulinate; mesaconate; pimelate; sebacate; suberate; norvaline; butylamine;
  • Active enzymes:
  • catalase;
    • SPECIAL FEATURES (Coenye2003a);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Nitrite:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Cephalosporins:
  • cefotaxime; cefpirom;
  • Macrolides:
  • azithromycin; clarithromycin; erythromycin; roxithromycin;
  • Quinolines:
  • ciprofloxacin; levofloxacin; ofloxacin; sparfloxacin;
  • Polypep/ketides:
  • rifampicin;

  • Coenye, T., Vancanneyt, M., Cnockaert, M. C., Falsen, E., Swings, J., & Vandamme, P. (2003). Kerstersia gyiorum gen. nov., sp. nov., a novel Alcaligenes faecalis-like organism isolated from human clinical samples, and reclassification of Alcaligenes denitrificans Rüger and Tan 1983 as Achromobacter denitrificans comb. nov. International Journal of Systematic and Evolutionary Microbiology, 53(Pt 6), 1825–1831.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Burkholderiales Family:  Alcaligenaceae Genus:  Kerstersia Gram stain:  neg Spore:  No spore Motility:  vr Morphology:  Coccus
    Health:  Unknown
    Source:  clinical sources (sputum, wound - CCUG) and human faeces (CCUG)
    DNA G+C(%):  62.7-62.9
    Opt. T:  33-37℃
    Lower T(℃):  28(+)
    High T(℃):  42(+)
    NaCl 0.5-2%:  0.5(+)
    NaCl 3-5%:  4.5(+)
    NaCl >6%:  6.0(neg)
    		Aesculin:  neg Urea:  neg Gelatin:  neg Starch:  neg DNA:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Maltose:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg D-Lyxose:  neg Mannose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  d Gentiobiose:  d Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Raffinose:  neg Sucrose:  neg D-Turanose:  neg Trehalose:  neg N_Acetyl_glucosamine:  neg Adonitol:  neg Amygdalin:  neg D-Arabitol:  neg L-Arabitol:  neg Arbutin:  neg Dulcitol:  neg Erythritol:  neg Aesculin:  neg Ethanolamine:  neg Gluconate:  d Glucosamine:  neg Glycerol:  d Glycogen:  neg Inositol:  neg Inulin:  neg Mannitol:  neg Me-α-D-Glc:  neg Salicin:  neg Sorbitol:  neg Starch:  neg Xylitol:  neg Ala:  + D-Ala:  + β-Ala:  d 4-Aminobutyrate:  + 5-Aminovalerate:  neg Arg:  neg Asp:  + Betaine:  neg L-Citrulline:  neg Cys:  d Glu:  + Gly:  neg Histamine:  neg His:  neg Ile:  d DL-Kynurenine:  + Leu:  d Lys:  neg Met:  d Norleucine:  d Orn:  + Phe:  + Pro:  + Sarcosine:  neg Ser:  neg Thr:  d Trigonelline:  neg Tryptamine:  d Trp:  d Tyr:  + Val:  d Acetate:  + Aconitate:  d Adipate:  d Azelate:  d Benzoate:  neg Butyrate:  + Caprate:  + Caproate:  + Caprylate:  d Citraconate:  d Citrate:  + Fumarate:  + Glutarate:  d DL-Glycerate:  neg Glycolate:  neg Heptanoate:  + 3-Hydroxybutyrate:  + 3-Hydroxybenzoate:  neg 4-Hydroxybenzoate:  + Isobutyrate:  d Isovalerate:  d Itaconate:  d 2-Ketogluconate:  neg DL-Lactate:  + Levulinate:  d L-Malate:  + Malonate:  neg L-Mandelate:  neg Mesaconate:  d Nonanoate:  + Phenylacetate:  + Pimelate:  d Propionate:  + Pyruvate:  + Sebacate:  d Suberate:  d Succinate:  + D-Tartrate:  neg L-Tartrate:  neg Valerate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg ArgDH:  neg LysDC:  neg OrnDC:  neg DNAse:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    cefotaxime:  S(MIC50): 0.5, MIC90: 0.5, RNG: (0.25-1)
    cefpirom:  S(MIC50): 1, MIC90: 2, RNG: (1-8)
    azithromycin:  S(MIC50): 1, MIC90: 1, RNG: (0.5-1)
    erythromycin:  S(MIC50): 2, MIC90: 2, RNG: (2)
    clarithromycin:  S(MIC50): 2, MIC90: 2, RNG: (1-2)
    roxithromycin:  S(MIC50): 4, MIC90: 4, RNG: (2-4)
    ciprofloxacin:  S(MIC50): 1, MIC90: 1, RNG: (0.5-8)
    levofloxacin:  S(MIC50): 2, MIC90: 2, RNG: (1-16)
    ofloxacin:  S(MIC50): 4, MIC90: 4, RNG: (2-16)
    sparfloxacin:  S(MIC50): 0.5, MIC90: 0.5, RNG: (0.25-8)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    rifampicin:  R(MIC50): 16, MIC90: 32, RNG: (8-32)

    References

    SPECIFIC REFERENCES FOR KERSTERSIA GYIORUM
  • Coenye2003a - Kerstersia gyiorum gen. nov., sp. nov., a novel Alcaligenes faecalis-like organism isolated from human clinical samples, and reclassification of Alcaligenes denitrificans Ruger and Tan 1983 as Achromobacter denitrificans comb. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR KERSTERSIA GYIORUM
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR KERSTERSIA GYIORUM
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021