Klebsiella michiganensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Klebsiella michiganensis is a Gram-negative, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 54.6%. Klebsiella michiganensis is probably a common, although minor, coloniser of the gut. (Saha2012)



  • This organism has been recovered from human faeces, clinical sources (blood, urine - CCUG) and tooth brush holder. It is an opportunistic pathogen. A possible gut commensal.
    • QUIRKS
  • In 12% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Saha2012);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🧂
  • Salt tolerance:
  • tolerates 6% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 10; Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • grows at 10℃; grows at 45℃; Grows optimally at 35℃.
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; glucose; rhamnose; amygdalin; melezitose; sucrose; inositol; mannitol; sorbitol;
  • ⥅
  • Substrates assimilated or utilised:
  • glucose; inositol; lactose; mannitol; melibiose; rhamnose; sorbitol; sucrose;
  • Active enzymes:
  • catalase; β-galactosidase; lycine decarboxylase;
    • SPECIAL FEATURES (Saha2012);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Metabolites not produced:
  • H₂S;
  • ✗
  • Methyl red test:
  • not active
  • ✓
  • VP test:
  • active
  • ✓
  • Nitrate:
  • reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Enterobacterales Family:  Enterobacteriaceae Genus:  Klebsiella Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, clinical sources (blood, urine - CCUG) and tooth brush holder
    DNA G+C(%):  54.6
    Opt. T:  35℃
    Low T(℃):  10(+)
    High T(℃):  45(+)
    NaCl >6%:  6(+)
    Opt. pH:  7
    pH >8:  10(+)
    		Aesculin:  + Urea:  neg Gelatin:  neg Pectin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + Glucose:  + Rhamnose:  + Melezitose:  + Sucrose:  + Amygdalin:  + Inositol:  + Mannitol:  + Sorbitol:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Glucose:  + Rhamnose:  + Lactose:  + Melibiose:  + Sucrose:  + Dulcitol:  neg Inositol:  + Mannitol:  + Sorbitol:  + Histamine:  neg Orn:  neg Phe:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg β-Galactosidase:  + ArgDH:  neg LysDC:  + OrnDC:  neg TrpAA:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  +

    References

    SPECIFIC REFERENCES FOR KLEBSIELLA MICHIGANENSIS
  • Saha2012 - Klebsiella michiganensis sp. nov., A New Bacterium Isolated from a Tooth Brush Holder.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR KLEBSIELLA MICHIGANENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • King2019 - Baseline human gut microbiota profile in healthy people and standard reporting template.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • ...............................
    • Added: March 29, 2021