Kurthia massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Kurthia massiliensis is a Gram-positive, non-spore-forming, strictly aerobic, motile, coccobacillus bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 39.3%. Kurthia massiliensis is probably a rare gut coloniser. (Roux2012)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Roux2012);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 0.5-2.0% salt; tolerates 3-5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-8.0; tolerates pH 9; Grows optimally at pH 7.0-9.0.
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 55℃; Grows optimally at 25-50℃.
  • ⥅
  • Substrates assimilated or utilised:
  • gluconate; maltose; citrate;
  • Active enzymes:
  • catalase; cystine arylamidase; esterase C4; esterase lipase C8;
    • RESPONSE TO ANTIBIOTICS (Roux2012);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem; penicillin G;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • nitrofurantoin;
  • metronidazole; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Planococcaceae Genus:  Kurthia Gram stain:  + O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Swimming Morphology:  Coccobacillus
    Health:   Positive
    Source:  human faeces
    DNA G+C(%):  39.3
    Opt. T:  25-50℃
    Lower T(℃):  25(+)
    High T(℃):  55(+)
    NaCl 0.5-2%:  0.5-2.0(+)
    NaCl 3-5%:  3-5(+)
    Opt. pH:  7.0-9.0
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  9(+)
    		Gelatin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Maltose:  + N_Acetyl_glucosamine:  neg Gluconate:  + Citrate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Chymotrypsin:  w CystineAA:  + ValAA:  w AlkalineP:  neg Esterase(C4):  + EstLip(C8):  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    penicillin_G:  Sens
    imipenem:  Sens
    gentamicin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    metronidazole:  Res
    nitrofurantoin:  Sens
    SXT:  Res

    References

    SPECIFIC REFERENCES FOR KURTHIA MASSILIENSIS
  • Roux2012 - Non-contiguous finished genome sequence and description of Kurthia massiliensis sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR KURTHIA MASSILIENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR KURTHIA MASSILIENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021