Lachnoanaerobaculum orale

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Lachnoanaerobaculum orale is a Gram-positive, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 38%. Lachnoanaerobaculum orale is probably a rare gut coloniser. (Hedberg2012)



  • This organism has been recovered from the saliva of a healthy man. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Hedberg2012);
    Character Response
  • Substrates hydrolysed or digested:
  • urea;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 6.5-7.0.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • glucose;
  • Active enzymes:
  • α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase; pyroGlu arylamidase; urease;
    • SPECIAL FEATURES (Hedberg2012);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate (major); lactate; H₂S; ammonia; indole;
  • ✗
  • Haemolysis:
  • absent
    • RESPONSE TO ANTIBIOTICS (Hedberg2012);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Lachnoanaerobaculum Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  the saliva of a healthy man
    DNA G+C(%):  38
    Opt. T:  37℃
    Opt. pH:  6.5-7.0
    Bile reaction(%):  20(neg)
    		Urea:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Glucose:  + Mannose:  neg Raffinose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  + α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + PyrogluAA:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  Major(+) Lactate:  + H2S:  + Ammonia:  + Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  S(0.3)
    kanamycin:  S(1000; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(5; disc)
    metronidazole:  S(5; disc)
    colistin:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR LACHNOANAEROBACULUM ORALE
  • Hedberg2012 - Lachnoanaerobaculum gen. nov., a new genus in the Lachnospiraceae : characterization of Lachnoanaerobaculum umeaense gen. nov., sp. nov., isolated from the human small intestine, and Lachnoanaerobaculum orale sp. nov., isolated from saliva, and reclassification of Eubacterium saburreum (Prevot 1966) Holdeman and Moore 1970 as Lachnoanaerobaculum saburreum comb. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LACHNOANAEROBACULUM ORALE
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022