Lachnoanaerobaculum umeaense

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Lachnoanaerobaculum umeaense is a Gram-positive, spore-forming, strictly anaerobic, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 35.0%. Lachnoanaerobaculum umeaense is probably a rare gut coloniser. (Hedberg2012)



  • This organism has been recovered from human faeces, and human gut. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Hedberg2012);
    Character Response
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 6.5-7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 37℃;
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; glucose; mannose; xylose; lactose; maltose; melezitose; raffinose; sucrose; trehalose;
  • ⥅
  • Substrates assimilated or utilised:
  • arabinose; mannose; raffinose;
  • Active enzymes:
  • α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase;
    • SPECIAL FEATURES (Hedberg2012);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate; H₂S; ammonia;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent
    • RESPONSE TO ANTIBIOTICS (Hedberg2012);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

  • Hedberg, M. E., Moore, E. R. B., Svensson-Stadler, L., Höstedt, P., Baranov, V., Hernell, O., Wai, S. N., Hammarström, S., & Hammarström, M.-L. (2012). Lachnoanaerobaculum a new genus in Lachnospiraceae; characterization of Lachnoanaerobaculum umeaense gen. Int. J. Syst. Evol. Microbiol. Ijs, 0(v.), 033613–0.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Lachnoanaerobaculum Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, and human gut
    DNA G+C(%):  35.0
    Mid T(℃):  37(+)
    Opt. pH:  6.5-7.0
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + Glucose:  + Mannose:  + Xylose:  + Lactose:  + Maltose:  + Melezitose:  + Sucrose:  + Trehalose:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  + Mannose:  + Raffinose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + PyrogluAA:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  + H2S:  + Ammonia:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  S(0.06)
    kanamycin:  S(1000)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(5)
    metronidazole:  S(5)
    colistin:  R(10)

    References

    SPECIFIC REFERENCES FOR LACHNOANAEROBACULUM UMEAENSE
  • Hedberg2012 - Lachnoanaerobaculum gen. nov., a new genus in the Lachnospiraceae : characterization of Lachnoanaerobaculum umeaense gen. nov., sp. nov., isolated from the human small intestine, and Lachnoanaerobaculum orale sp. nov., isolated from saliva, and reclassification of Eubacterium saburreum (Prevot 1966) Holdeman and Moore 1970 as Lachnoanaerobaculum saburreum comb. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LACHNOANAEROBACULUM UMEAENSE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR LACHNOANAEROBACULUM UMEAENSE
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021