Lawsonella clevelandensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Lawsonella clevelandensis is a Gram-variable, non-spore-forming, strictly anaerobic, non-motile, pleiomorph rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 58.6%. Lawsonella clevelandensis is probably a rare gut coloniser. (Bell2016)



  • This organism has been recovered from a spinal abscess. Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Bell2016);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; doesn't grow at 45℃; Grows optimally at 35℃.
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  • Substrates assimilated or utilised:
  • galactose; glucose; glycerol; lactose; maltose; sucrose;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Lawsonellaceae Genus:  Lawsonella Gram stain:  vr O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Pleiomorph rod
    Health:  Unknown
    Source:  a spinal abscess
    DNA G+C(%):  58.6
    Opt. T:  35℃
    Lower T(℃):  25(+)
    High T(℃):  45(neg)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  neg Galactose:  + Glucose:  + Mannose:  neg Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  + Maltose:  + Sucrose:  + Trehalose:  neg Erythritol:  neg Glycerol:  + Inositol:  neg Mannitol:  neg Sorbitol:  neg

    References

    SPECIFIC REFERENCES FOR LAWSONELLA CLEVELANDENSIS
  • Bell2016 - Lawsonella clevelandensis gen. nov., sp. nov., a new member of the suborder Corynebacterineae isolated from human abscesses.
  • Nicholson2015a - Complete Genome Sequences for Two Strains of a Novel Fastidious, Partially Acid-Fast, Gram-Positive Corynebacterineae Bacterium, Derived from Human Clinical Samples.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LAWSONELLA CLEVELANDENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • New2022 - Collective effects of human genomic variation on microbiome function.
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    • Added: January 19, 2022