Lawsonia intracellularis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Lawsonia intracellularis is a Gram-negative, non-spore-forming, microaerophilic, non-motile, rod-shaped - curved bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Lawsonia intracellularis is likely to be transient and not a long-term gut coloniser. (McOrist1995)



  • This organism has been recovered from epithelial cells in the ilea of pigs. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: opportunistic in immunocompromised patients). Could be a possible pathogen in humans, but unknown at this stage. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Intracellular pathogen of pigs.
    • GENERAL CHARACTERISTICS
    Character Response
    SPECIAL FEATURES (McOrist1995);
    Character Response
  • ✗
  • Sulfate:
  • not reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant

    Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Deltaproteobacteria Order:  Desulfovibrionales Family:  Desulfovibrionaceae Genus:  Lawsonia Gram stain:  neg O2 Relation.:  microaerophilic Spore:  No spore Motility:  Sessile Morphology:  Rod - curved Pigment:  neg
    Health:  Unknown
    Source:  epithelial cells in the ilea of pigs
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    chlortetracycline:  Var(MIC50): 0.125-64), MIC90: Var(0.125-64

    References

    SPECIFIC REFERENCES FOR LAWSONIA INTRACELLULARIS
  • McOrist1995 - Characterization of Lawsonia intracellularis gen. nov., sp. nov., the obligately intracellular bacterium of porcine proliferative enteropathy.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LAWSONIA INTRACELLULARIS
  • New2022 - Collective effects of human genomic variation on microbiome function.
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    • Added: March 18, 2022