Lawsonibacter asaccharolyticus

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Lawsonibacter asaccharolyticus is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 61.2%. Lawsonibacter asaccharolyticus is a common gut coloniser. (Sakamoto2018a)



  • This organism has been recovered from human faeces (Sakamoto2018a). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 97% of Europeans (unseenbio.com).
    • GENERAL CHARACTERISTICS (Sakamoto2018a);
    Character Response
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-8.0; Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 45℃; Grows optimally at 37℃.
  • Active enzymes:
  • alkaline phosphatase; esterase; esterase lipase C8; naphthol-ASBI-P;
    • SPECIAL FEATURES (Sakamoto2018a);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Sakamoto2018a);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • oxytetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin; kanamycin; neomycin; streptomycin;
  • Polypep/ketides:
  • bacitracin;
  • Heterocycles:
  • chloramphenicol;
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Eubacteriales incertae sedis Genus:  Lawsonibacter Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces (Sakamoto2018a)
    DNA G+C(%):  61.2
    Opt. T:  37℃
    Lower T(℃):  30(+)
    High T(℃):  45(+)
    Opt. pH:  7
    pH 6.0-8.0:  6.0-8.0(+)
    Bile reaction(%):  20(neg)
    		Aesculin:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Glucose:  w Mannose:  neg Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Sucrose:  neg Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  neg ArgAA:  w CystineAA:  neg GluGluAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  w LeuGlyAA:  neg ProAA:  neg PheAA:  neg PyrogluAA:  neg TyrAA:  w ValAA:  neg AlkalineP:  + Esterase:  + EstLip(C8):  + Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  + H2S:  neg Indole:  neg Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    penicillin:  Sens
    gentamicin:  Res
    kanamycin:  Res
    neomycin:  Res
    streptomycin:  Res
    erythromycin:  Sens
    ciprofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    oxytetracycline:  Sens
    vancomycin:  Sens
    bacitracin:  Sens
    chloramphenicol:  Sens
    SXT:  Res
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR LAWSONIBACTER ASACCHAROLYTICUS
  • Sakamoto2018 - Draft Genome Sequence of Lawsonibacter asaccharolyticus JCM 32166 T , a Butyrate-Producing Bacterium, Isolated from Human Feces.
  • Sakamoto2018a - Lawsonibacter asaccharolyticus gen. nov., sp. nov., a butyrate-producing bacterium isolated from human faeces.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LAWSONIBACTER ASACCHAROLYTICUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • ...............................
    • GENERAL REFERENCES FOR LAWSONIBACTER ASACCHAROLYTICUS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: July 12, 2021