Lederbergia galactosidilyticus

(aka Bacillus galactosidilyticus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Lederbergia galactosidilyticus, (aka Bacillus galactosidilyticus), is a Gram-positive, spore-forming, facultatively anaerobic, motile, short rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 35.7-38.2%. Lederbergia galactosidilyticus is probably a rare gut coloniser. (Heyndrickx2004)



  • This organism has been recovered from raw milk. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Heyndrickx2004);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • urea;
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 5.0; tolerates pH 6.0; tolerates pH 10.5;
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 40℃; doesn't grow at 50℃; Grows optimally at 25-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; N-Ac glucosamine;
  • ±
  • Strain-dependent acid from carbs:
  • L-arabinose; galactose; mannose; rhamnose; ribose; xylose; amygdalin; inulin; starch; cellubiose; gentiobiose; lactose; maltose; melezitose; melibiose; raffinose; sucrose; trehalose; D-turanose; mannitol; arbutin; α-methyl glucoside; salicin;
  • Active enzymes:
  • catalase; β-galactosidase;
  • ±
  • Strain-dependent active enzymes:
  • urease;
    • SPECIAL FEATURES (Heyndrickx2004);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • VP test:
  • not active
  • ✓
  • ONPG test:
  • active
  • ✓
  • NO3➔NO2:
  • reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Bacillaceae Genus:  Lederbergia Alt. name:  Bacillus galactosidilyticus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Short Rod
    Health:  Unknown
    Source:  raw milk
    DNA G+C(%):  35.7-38.2
    Opt. T:  25-37℃
    Lower T(℃):  30(+)
    Mid T(℃):  40(+)
    High T(℃):  50(neg)
    pH 4.2-5.9:  5.0(neg)
    pH 6.0-8.0:  6.0(+)
    pH >8:  10.5(+)
    		Aesculin:  + Urea:  d Gelatin:  neg Casein:  w
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  d Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  d Glucose:  + Mannose:  d D-Lyxose:  neg Rhamnose:  d Ribose:  d Sorbose:  neg D-Tagatose:  neg Xylose:  d L-Xylose:  neg Cellubiose:  d Gentiobiose:  d Lactose:  d Maltose:  d Melezitose:  d Melibiose:  d Sucrose:  d Trehalose:  d Turanose:  d Amygdalin:  d Glycogen:  neg Inulin:  d Starch:  d Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  d Sorbitol:  neg Xylitol:  neg Arbutin:  d Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  d Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  + Salicin:  d
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Citrate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  d β-Galactosidase:  + ArgDH:  neg LysDC:  neg OrnDC:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR LEDERBERGIA GALACTOSIDILYTICUS
  • Gupta2020a - Robust demarcation of 17 distinct Bacillus species clades, proposed as novel Bacillaceae genera, by phylogenomics and comparative genomic analyses: description of Robertmurraya kyonggiensis sp. nov. and proposal for an emended genus Bacillus limiting it only to the members of the Subtilis and Cereus clades of species.
  • Heyndrickx2004 - Bacillus galactosidilyticus sp. nov., an alkali-tolerant beta-galactosidase producer.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LEDERBERGIA GALACTOSIDILYTICUS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022