Ligilactobacillus agilis

(aka Lactobacillus agilis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Ligilactobacillus agilis, (aka Lactobacillus agilis), is a Gram-positive, non-spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 43–44%. Ligilactobacillus agilis is probably a rare gut coloniser. (Hammes2011eBergey; Baele2001; Weiss1981)



  • This organism has been recovered from animal faeces, sewage. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Hammes2011eBergey); (Baele2001); (Weiss1981);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; hippurate; mucin;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 15℃; grows at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; ribose; amygdalin; cellubiose; gentiobiose; maltose; melezitose; melibiose; raffinose; sucrose; trehalose; mannitol; arbutin; N-Ac glucosamine; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • melibiose; mucin;
  • Active enzymes:
  • Ala-Phe-Pro arylamidase; N-Ac β-glucosaminidase; β-galactosidase; β-glucosidase; pyrrolidine arylamidase;
    • SPECIAL FEATURES (Hammes2011eBergey); (Weiss1981);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✓
  • VP test:
  • active

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Lactobacillaceae Genus:  Ligilactobacillus Alt. name:  Lactobacillus agilis Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  animal faeces, sewage
    DNA G+C(%):  43–44
    Low T(℃):  15(neg)
    High T(℃):  45(+)
    		Aesculin:  + Urea:  neg Gelatin:  neg Casein:  neg Arginine:  neg Hippurate:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  + Sorbose:  vr Xylose:  neg L-Xylose:  neg Cellubiose:  + Gentiobiose:  + Maltose:  + Melezitose:  + Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  neg Amygdalin:  + Dextrin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  + Sorbitol:  neg Xylitol:  neg Arbutin:  + Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  + Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg Ac-β-glcamnd:  + α-Galactosidase:  neg β-Galactosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg β-Mannosidase:  neg ArgDH:  neg AlaPheProAA:  + PyrrolidAA:  + AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  + H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR LIGILACTOBACILLUS AGILIS
  • Zheng2020 - A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae.
  • Hammes2011eBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Lactobacillaceae, Genus I. Ligilactobacillus
  • Baele2001 - Lactobacillus agilis is an important component of the pigeon crop flora.
  • Weiss1981 - Lactobacillus sharpeae sp. nov. and Lactobacillus agilis sp. nov., two new species of homofermentative, meso-diaminopimelic acid-containing lactobacilli isolated from sewage.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LIGILACTOBACILLUS AGILIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • PerezBrocal2015 - Metagenomic Analysis of Crohn's Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • ...............................
    • GENERAL REFERENCES FOR LIGILACTOBACILLUS AGILIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 22, 2021