Ligilactobacillus murinus

(aka Lactobacillus murinus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Ligilactobacillus murinus, (aka Lactobacillus murinus), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 43-44%. Ligilactobacillus murinus is probably a rare gut coloniser. (Hammes2011eBergey; Heeney2017; Rossi2016; Hemme1980)



  • This organism has been recovered from human faeces, sourdough, clinical sources (blood, drainage fluid, skin infection - CCUG) and animal intestines. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. It is an opportunistic pathogen. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • In 1% of Europeans (unseenbio.com). Rare coloniser.
    • GENERAL CHARACTERISTICS (Hammes2011eBergey); (Hemme1980);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 6% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 15℃; grows at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • aesculin; cellubiose; melibiose; raffinose; sucrose;
  • ±
  • Strain-dependent acid from carbs:
  • amygdalin; mannitol;
  • ⥅
  • Substrates assimilated or utilised:
  • malate;
    • SPECIAL FEATURES (Hammes2011eBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Lactobacillaceae Genus:  Ligilactobacillus Alt. name:  Lactobacillus murinus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, sourdough, clinical sources (blood, drainage fluid, skin infection - CCUG) and animal intestines
    DNA G+C(%):  43-44
    Low T(℃):  15(neg)
    High T(℃):  45(+)
    NaCl >6%:  6(+)
    		Urea:  neg Gelatin:  neg Casein:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  w D-Lyxose:  neg Ribose:  w Xylose:  neg Cellubiose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Amygdalin:  d Aesculin:  + Mannitol:  d Sorbitol:  neg Gluconate:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Malate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  + H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR LIGILACTOBACILLUS MURINUS
  • Zheng2020 - A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae.
  • Hammes2011eBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Lactobacillaceae, Genus I. Ligilactobacillus
  • Heeney2017 - Intestinal Lactobacillus in health and disease, a driver or just along for the ride?
  • Rossi2016 - Mining metagenomic whole genome sequences revealed subdominant but constant Lactobacillus population in the human gut microbiota.
  • Hemme1980 - Lactobacillus murinus N. Sp., une nouvelle espèce de la flore dominante autochtone du tube digestif du rat et de la souris ["Lactobacillus murinus" n. sp., a new species of the autochtoneous dominant flora of the digestive tract of rat and mouse (author's transl)].
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LIGILACTOBACILLUS MURINUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: December 15, 2021