Limosilactobacillus antri

(aka Lactobacillus antri)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Limosilactobacillus antri, (aka Lactobacillus antri), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 6 gut microbiome compilation studies or metastudies. The DNA G+C content is 44.9%. Limosilactobacillus antri is probably a rare gut coloniser. (Hammes2011fBergey; Roos2005)



  • This organism has been recovered from human faeces, and human gastric mucosa. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Hammes2011fBergey); (Roos2005);
    Character Response
  • Substrates hydrolysed or digested:
  • hippurate;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; L-arabinose; fructose; galactose; glucose; ribose; maltose; melibiose; raffinose; sucrose; D-arabitol; gluconate;
  • ±
  • Strain-dependent acid from carbs:
  • xylose;
  • ⥅
  • Substrates assimilated or utilised:
  • melibiose;
  • Active enzymes:
  • alkaline phosphatase; α-galactosidase;
    • SPECIAL FEATURES (Hammes2011fBergey); (Roos2005);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate (major);
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✓
  • VP test:
  • active
    • RESPONSE TO ANTIBIOTICS (Citron2012a);
    Class Active Resistant
  • Penicillins:
  • ampicillin; ampicillin-sulbactam; imipenem; piperacillin-tazobactam;
  • Cephalosporins:
  • cefoxitin;
  • Macrolides:
  • fidaxomicin;
  • Quinolines:
  • moxifloxacin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;

  • Mitsuoka, T (1969). Vergleichende Untersuchungen über die Laktobazillen aus den Faeces von Menschen, Schweinen und Hühnern. Zbl. Bakt. Parasit. 210.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Lactobacillaceae Genus:  Limosilactobacillus Alt. name:  Lactobacillus antri Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, and human gastric mucosa
    DNA G+C(%):  44.9
    Lower T(℃):  25(+)
    High T(℃):  45(+)
    		Aesculin:  w Urea:  neg Gelatin:  neg Casein:  neg Hippurate:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + D-Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  d L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Turanose:  w Amygdalin:  neg Dextrin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  + L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  w Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  + 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  w Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg Ac-β-glcamnd:  neg α-Galactosidase:  + β-Galactosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg β-Mannosidase:  neg ArgDH:  neg AlaPheProAA:  neg PyrrolidAA:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  Major(+) H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  S(MIC50): 0.5, MIC90: 2, RNG: (0.06–4)
    amp-sulb:  S(MIC50): 0.5, MIC90: 2, RNG: (0.06–4)
    piper-taz:  S(MIC50): 1, MIC90: 4, RNG: (0.06–16)
    imipenem:  S(MIC50): 0.25, MIC90: 2, RNG: (0.25–4)
    cefoxitin:  R(MIC50): >32, MIC90: >32, RNG: (0.25–>32)
    fidaxomicin:  R(MIC50): 8, MIC90: >32, RNG: (0.015->32)
    moxifloxacin:  S(MIC50): 0.25, MIC90: 1, RNG: (0.125–8)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  R(MIC50): >64, MIC90: >64, RNG: (0.25–>64)
    metronidazole:  R(MIC50): >64, MIC90: >64, RNG: (0.125–>64)
    clindamycin:  S(MIC50): 0.125, MIC90: 2, RNG: (0.06–4)

    References

    SPECIFIC REFERENCES FOR LIMOSILACTOBACILLUS ANTRI
  • Zheng2020 - A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae.
  • Hammes2011fBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Lactobacillaceae, Genus I. Limosilactobacillus
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Citron2012a - Comparative in vitro activities of LFF571 against Clostridium difficile and 630 other intestinal strains of aerobic and anaerobic bacteria.
  • Roos2005 - Lactobacillus gastricus sp. nov., Lactobacillus antri sp. nov., Lactobacillus kalixensis sp. nov. and Lactobacillus ultunensis sp. nov., isolated from human stomach mucosa.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LIMOSILACTOBACILLUS ANTRI
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • GENERAL REFERENCES FOR LIMOSILACTOBACILLUS ANTRI
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021