Limosilactobacillus mucosae

(aka Lactobacillus mucosae)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Limosilactobacillus mucosae, (aka Lactobacillus mucosae), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 13 gut microbiome compilation studies or metastudies. The DNA G+C content is 46.5%. Limosilactobacillus mucosae is probably a rare gut coloniser. (Hammes2011fBergey; Rossi2016; Roos2000)



  • This organism has been recovered from pig intestine, sourdough and human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • In 4% of Europeans (unseenbio.com), i.e., a rare coloniser.
    • GENERAL CHARACTERISTICS (Hammes2011fBergey); (Roos2000);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; arginine;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 15℃; grows at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; ribose; xylose; aesculin; maltose; melibiose; raffinose; sucrose; gluconate; methyl xyloside;
  • ±
  • Strain-dependent acid from carbs:
  • L-arabinose; galactose; lactose;
  • ⥅
  • Substrates assimilated or utilised:
  • melibiose;
  • Active enzymes:
  • α-galactosidase; β-galactosidase;
    • SPECIAL FEATURES (Hammes2011fBergey); (Roos2000);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate (major);
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • VP test:
  • not active

  • Decroos, K., Vanhemmens, S., Cattoir, S., Boon, N., & Verstraete, W. (2005). Isolation and characterisation of an equol-producing mixed microbial culture from a human faecal sample and its activity under gastrointestinal conditions. Archives of Microbiology, 183(1), 45–55.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Lactobacillaceae Genus:  Limosilactobacillus Alt. name:  Lactobacillus mucosae Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  pig intestine, sourdough and human faeces
    DNA G+C(%):  46.5
    Low T(℃):  15(neg)
    High T(℃):  45(+)
    		Aesculin:  + Urea:  neg Gelatin:  neg Casein:  neg Arginine:  + Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  vr L-Arabinose:  d Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  d Glucose:  + Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  d(neg) Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Turanose:  neg Amygdalin:  neg Dextrin:  neg Aesculin:  + Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  + 2-Ketogluconate:  vr 5-Ketogluconate:  vr Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  + NAc-α-GA:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  d(+)
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Galactosidase:  + β-Galactosidase:  + β-Glucosidase:  vr β-Glucuronidase:  neg β-Mannosidase:  neg ArgDH:  neg AlaPheProAA:  neg PyrrolidAA:  neg AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  Major(+) H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR LIMOSILACTOBACILLUS MUCOSAE
  • Zheng2020 - A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae.
  • Hammes2011fBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Lactobacillaceae, Genus I. Limosilactobacillus
  • Rossi2016 - Mining metagenomic whole genome sequences revealed subdominant but constant Lactobacillus population in the human gut microbiota.
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Huang2019 - Analysis of microbiota in elderly patients with Acute Cerebral Infarction
  • Li2019b - Disordered intestinal microbes are associated with the activity of Systemic Lupus Erythematosus
  • Li2019c - Gut Microbiota Differs Between Parkinson's Disease Patients and Healthy Controls in Northeast China
  • Nobili2018 - Bifidobacteria and lactobacilli in the gut microbiome of children with non-alcoholic fatty liver disease: which strains act as health players?
  • Shimizu2019 - Relative abundance of Megamonas hypermegale and Butyrivibrio species decreased in the intestine and its possible association with the T cell aberration by metabolite alteration in patients with Behcet's disease
  • Wang2019 - Differential composition of gut microbiota among healthy volunteers, morbidly obese patients and post-bariatric surgery patients
  • Roos2000 - Lactobacillus mucosae sp. nov., a new species with in vitro mucus-binding activity isolated from pig intestine.
  • Petrov2017 - Analysis of Gut Microbiota in Patients with Parkinson's Disease.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LIMOSILACTOBACILLUS MUCOSAE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Li2019b - Disordered intestinal microbes are associated with the activity of Systemic Lupus Erythematosus
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • PerezBrocal2015 - Metagenomic Analysis of Crohn's Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • ...............................
    • GENERAL REFERENCES FOR LIMOSILACTOBACILLUS MUCOSAE
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021