Loigolactobacillus bifermentans

(aka Lactobacillus bifermentans)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Loigolactobacillus bifermentans, (aka Lactobacillus bifermentans), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, short rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 45%. Loigolactobacillus bifermentans is likely to be transient and not a long-term gut coloniser. (Kandler1983a)



  • This organism has been recovered from in Edam and Gouda cheeses. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Kandler1983a);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; doesn't grow at 42℃; Grows optimally at 30℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; rhamnose; ribose; maltose; mannitol;
  • ±
  • Strain-dependent acid from carbs:
  • sorbitol;
  • ⥅
  • Substrates assimilated or utilised:
  • lactate;
    • SPECIAL FEATURES (Kandler1983a);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate (trace); ethanol; CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Goldstein2013);
    Class Active Resistant
  • Penicillins:
  • imipenem; piperacillin-tazobactam;
  • Quinolines:
  • moxifloxacin;
  • Heterocycles:
  • metronidazole;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Lactobacillaceae Genus:  Loigolactobacillus Alt. name:  Lactobacillus bifermentans Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Short Rod
    Health:  Unknown
    Source:  in Edam and Gouda cheeses
    DNA G+C(%):  45
    Opt. T:  30℃
    Low T(℃):  15(+)
    High T(℃):  42(neg)
    		Urea:  neg Arginine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Ribose:  + Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Amygdalin:  neg Aesculin:  neg Starch:  neg Mannitol:  + Sorbitol:  d Gluconate:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Lactate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  trace(+) Ethanol:  + H2S:  neg CO2:  + H2:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    piper-taz:  S(MIC50): 1, MIC90: 4, RNG: (0.015–4)
    imipenem:  S(MIC50): 0.5, MIC90: 4, RNG: (0.03–16)
    moxifloxacin:  S(MIC50): 0.5, MIC90: 8, RNG: (0.25–16)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    metronidazole:  R(MIC50): >32, MIC90: >32, RNG: (2–>32)

    References

    SPECIFIC REFERENCES FOR LOIGOLACTOBACILLUS BIFERMENTANS
  • Goldstein2013 - In vitro activity of Biapenem plus RPX7009, a carbapenem combined with a serine β-lactamase inhibitor, against anaerobic bacteria.
  • Kandler1983a - Lactobacillus bifermentans sp. nov., nom. rev., an Organism Forming CO2 and H2 from Lactic Acid
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LOIGOLACTOBACILLUS BIFERMENTANS
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: April 05, 2022