Lutispora thermophila

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Lutispora thermophila is a Gram-negative, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 36.2%. Lutispora thermophila is likely to be transient and not a long-term gut coloniser. (Shiratori2008)



  • This organism has been recovered from a thermophilic methanogenic bioreactor digesting municipal solid wastes, Japan. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • A high optimum growth temperature (55-58C) suggests this is an unlikely gut coloniser.
    • GENERAL CHARACTERISTICS (Shiratori2008);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 0-2.0% salt; Grows optimally with 0% salt.
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0; tolerates pH 9; Grows optimally at pH 7.5-8.0.
  • 🌡
  • Temperature tolerance:
  • grows at 40℃; grows at 60℃; Grows optimally at 55-58℃.
  • ⥅
  • Substrates assimilated or utilised:
  • cysteine; lysine; methionine; serine; threonine; tryptophan; pyruvate; Casamino acids;
    • SPECIAL FEATURES (Shiratori2008);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; isobutyrate; isovalerate; Hâ‚‚S; indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Sulfate:
  • not reduced
  • ✗
  • Thiosulfate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Shiratori2008);
    Class Active Resistant
  • Aminoglycosides:
  • neomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Lutispora Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  a thermophilic methanogenic bioreactor digesting municipal solid wastes, Japan
    DNA G+C(%):  36.2
    Opt. T:  55-58℃
    Mid T(℃):  40(+)
    High T(℃):  60(+)
    NaCl 0.5-2%:  0-2.0(+)
    Opt. pH:  7.5-8.0
    pH 6.0-8.0:  6.0(+)
    pH >8:  9(+)
    		Aesculin:  w Gelatin:  w Casein:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Glucose:  neg Cys:  + Lys:  + Met:  + Ser:  + Thr:  + Trp:  + Fumarate:  neg Pyruvate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  + Isobutyrate:  + Isovalerate:  + H2S:  + Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    neomycin:  R(50; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)

    References

    SPECIFIC REFERENCES FOR LUTISPORA THERMOPHILA
  • Shiratori2008 - Lutispora thermophila gen. nov., sp. nov., a thermophilic, spore-forming bacterium isolated from a thermophilic methanogenic bioreactor digesting municipal solid wastes.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LUTISPORA THERMOPHILA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
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    • Added: May 15, 2022