General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview


  • Lysinibacillus meyeri is a Gram-positive, spore-forming, strictly aerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 37.1%. Lysinibacillus meyeri is likely to be transient and not a long-term gut coloniser. (Seiler2013)



  • This organism has been recovered from a medical practise. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.

  • QUIRKS
  • Obligate aerobe; unlikely to be a gut coloniser.

  • GENERAL CHARACTERISTICS (Seiler2013);
    Character Response
  • Substrates hydrolysed or digested:
  • casein; DNA; gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt; tolerates 5.5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.5; tolerates pH 8.5; Grows optimally at pH 7-8.
  • 🌡
  • Temperature tolerance:
  • grows at 10℃; grows at 42℃; Grows optimally at 30℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glycerol; mannitol; gluconate; 5-ketogluconate;
  • Substrates assimilated or utilised:
  • cellubiose; fructose; gluconate; glucose; glycerol; mannitol; 2-ketogluconate; 5-ketogluconate;
  • Active enzymes:
  • alkaline phosphatase; catalase; DNase; esterase lipase C8; oxidase; pyroGlu arylamidase;

  • SPECIAL FEATURES (Seiler2013);
    Character Response
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • VP test:
  • active
  • Nitrate:
  • not reduced
  • NO3➔NO2:
  • not reduced

  • RESPONSE TO ANTIBIOTICS (Seiler2013);
    Class Active Resistant
  • Penicillins:
  • carbenicillin; penicillin G;
  • ampicillin;
  • Cephalosporins:
  • cefepime; ceftazidime; cephalothin;
  • Macrolides:
  • oleandomycin;
  • Tetracyclines:
  • tetracycline;
  • Aminoglycosides:
  • kanamycin; neomycin;
  • Miscellaneous antibiotics:
  • lincomycin; polymyxin B;

  • Details


    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Caryophanales Family:  Caryophanaceae Genus:  Lysinibacillus Gram stain:  + O2 Relation.:  strictly aerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  a medical practise
    DNA G+C(%):  37.1
    Opt. T:  30℃
    Low T(℃):  10(+)
    High T(℃):  42(+)
    NaCl 0.5-2%:  0(+)
    NaCl >6%:  5.5(+)
    Opt. pH:  7-8
    pH 6.0-8.0:  6.5(+)
    pH >8:  8.5(+)
    Aesculin:  neg Urea:  neg Gelatin:  + Starch:  neg Casein:  + DNA:  + Tyrosine:  neg Tween:  20(+) 40(+) 60(+) 80(neg)

    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Amygdalin:  neg Aesculin:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  + Inositol:  neg Mannitol:  + Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  + 2-Ketogluconate:  neg 5-Ketogluconate:  + Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg

    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Glucose:  + D-Lyxose:  neg Sorbose:  neg D-Tagatose:  neg Cellubiose:  + Gentiobiose:  neg Lactose:  neg Melezitose:  neg Raffinose:  neg D-Turanose:  neg N_Acetyl_glucosamine:  neg Adonitol:  neg Amygdalin:  neg D-Arabitol:  neg L-Arabitol:  neg Arbutin:  neg Dulcitol:  neg Erythritol:  neg Gluconate:  + Glycerol:  + Glycogen:  neg Inositol:  neg Inulin:  neg Mannitol:  + Me-α-D-Glc:  neg Salicin:  neg Sorbitol:  neg Starch:  neg Xylitol:  neg Citrate:  neg 2-Ketogluconate:  + 5-Ketogluconate:  +

    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Phe deaminase:  neg TrpAA:  neg PyrogluAA:  + ValAA:  neg AlkalineP:  + AcidP:  neg DNAse:  + Esterase(C4):  neg EstLip(C8):  + Lecithinase:  neg Lipase(C14):  neg

    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    H2S:  neg Indole:  neg

    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Res
    carbenicil:  Sens
    penicillin_G:  Sens
    cefepime:  R(8)
    ceftazidime:  R(8)
    cephalothin:  Res
    kanamycin:  Sens
    neomycin:  Sens
    oleandomycin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Sens
    lincomycin:  Res
    polymyxin_B:  Res

    References


    SPECIFIC REFERENCES FOR LYSINIBACILLUS MEYERI
  • Seiler2013 - Lysinibacillus meyeri sp. nov., isolated from a medical practice.
  • ...............................
  • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR LYSINIBACILLUS MEYERI
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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