Mammaliicoccus sciuri

(aka Staphylococcus sciuri)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Mammaliicoccus sciuri, (aka Staphylococcus sciuri), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 32.7%. Mammaliicoccus sciuri is probably a rare gut coloniser. (Madhaiyan2020; Kloos1976; Webster1994; Schleifer2011Bergey)



  • This organism has been recovered from animal, soil, water sources and human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Kloos1976); (Webster1994); (Schleifer2011Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; casein; DNA; gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 6-10% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; doesn't grow at 45℃; Grows optimally at 35-40℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; ribose; cellubiose; maltose; sucrose; D-turanose; mannitol; N-Ac glucosamine;
  • ⥅
  • Substrates assimilated or utilised:
  • fructose; galactose; gentiobiose; glucose; glycerol; mannitol; ribose; sorbitol; sucrose; trehalose;
  • ±
  • Strain-dependent substrate utilisation:
  • L-arabinose; maltose; mannose; melezitose; rhamnose; salicin; xylose;
  • Active enzymes:
  • acid phosphatase; catalase; DNase; esterase C4; esterase lipase C8; α-glucosidase; β-glucosidase; oxidase;
  • ±
  • Strain-dependent active enzymes:
  • alkaline phosphatase;
    • SPECIAL FEATURES (Kloos1976); (Webster1994); (Schleifer2011Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • ✗
  • VP test:
  • not active
  • Haemolysis:
  • present but weak
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Goldstein2006b); (Kloos1976); (Webster1994);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; ertapenem; imipenem; meropenem; penicillin; piperacillin-tazobactam;
  • Cephalosporins:
  • cefotetan;
  • Macrolides:
  • erythromycin; quinupristin-dalfopristin;
  • Tetracyclines:
  • doxycycline; tigecycline;
  • Heterocycles:
  • co-trimoxazole; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin; dalbavancin;
  • Miscellaneous antibiotics:
  • daptomycin; linezolid;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Staphylococcaceae Genus:  Mammaliicoccus Alt. name:  Staphylococcus sciuri Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  animal, soil, water sources and human faeces
    DNA G+C(%):  32.7
    Opt. T:  35-40℃
    Low T(℃):  15(+)
    High T(℃):  45(neg)
    NaCl >6%:  6-10(+)
    		Aesculin:  + Urea:  neg Gelatin:  + Casein:  + DNA:  + Tween:  80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  vr Fructose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Ribose:  + Xylose:  neg Cellubiose:  + Lactose:  vr Maltose:  + Sucrose:  + Turanose:  + Glycogen:  neg Mannitol:  + NAc-α-GA:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  d Fructose:  + Fucose:  neg Galactose:  + Glucose:  + D-Lyxose:  neg Mannose:  d Rhamnose:  d Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  d Cellubiose:  w Gentiobiose:  + Maltose:  d Melezitose:  d Melibiose:  neg Raffinose:  neg Sucrose:  + D-Turanose:  neg Trehalose:  + N_Acetyl_glucosamine:  neg Adonitol:  neg D-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  + Inositol:  neg Mannitol:  + Salicin:  d Sorbitol:  + Xylitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Coagulase:  neg HS nuclease:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg OrnDC:  neg LeuAA:  neg PyrrolidAA:  neg AlkalineP:  d AcidP:  + DNAse:  + Esterase(C4):  + EstLip(C8):  + Lipase:  neg Lipase(C14):  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  S(MIC50): 0.125, MIC90: 4, RNG: (0.06–8)
    oxacillin:  Var(MIC50): >2, MIC90: >2, RNG: (≤0.06->2)
    penicillin:  S(MIC50): 8, MIC90: 8, RNG: (0.06–8)
    penicillin_G:  Var(MIC50): 0.2-6.2), MIC90: Var(0.2-6.2
    piper-taz:  S(MIC50): 0.5, MIC90: 16, RNG: (0.125–32)
    ertapenem:  S(0.5/4)
    imipenem:  S(MIC50): 0.06, MIC90: 0.125, RNG: (0.06–0.25)
    meropenem:  S(MIC50): 0.125, MIC90: 4, RNG: (0.06–8)
    cefotetan:  S(MIC50): 16, MIC90: 32, RNG: (8–32)
    erythromycin:  SensRNG: (0.4-1.6)
    quin-dalf:  S(MIC50): 0.25, MIC90: 0.5, RNG: (≤0.25->8)
    linezolid:  S(MIC50): 1, MIC90: 1, RNG: (0.12-2)
    levofloxacin:  Var(MIC50): >2, MIC90: >4, RNG: (≤0.03->4)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(≤2/4)
    tetracycline:  Var(MIC50): 0.4-6.2), MIC90: Var(0.4-6.2
    tigecycline:  S(MIC50): 0.25, MIC90: 0.5, RNG: (0.03-1)
    dalbavancin:  S(MIC50): 0.125, MIC90: 0.25, RNG: (0.016–2)
    teicoplanin:  Var(MIC50): 2, MIC90: 8, RNG: (≤2->16)
    vancomycin:  S(MIC50): 1, MIC90: 2, RNG: (0.25-4)
    SXT:  S(≤0.5/1)
    co-trimoxazole:  S(MIC50): >1, MIC90: >2, RNG: (≤0.5->2)
    clindamycin:  Var(MIC50): >0.12, MIC90: >8, RNG: (≤0.06->8)
    daptomycin:  S(MIC50): 0.25, MIC90: 0.5, RNG: (0.06-2)
    novobiocin:  Var(MIC50): 1.6-12.5), MIC90: Var(1.6-12.5

    References

    SPECIFIC REFERENCES FOR MAMMALIICOCCUS SCIURI
  • Madhaiyan2020 - Phylogenomic analyses of the Staphylococcaceae family suggest the reclassification of five species within the genus Staphylococcus as heterotypic synonyms, the promotion of five subspecies to novel species, the taxonomic reassignment of five Staphylococcus species to Mammaliicoccus gen. nov., and the formal assignment of Nosocomiicoccus to the family Staphylococcaceae
  • Goldstein2006b - In vitro activities of dalbavancin and 12 other agents against 329 aerobic and anaerobic gram-positive isolates recovered from diabetic foot infections.
  • Kloos1976 - Characterization of Staphylococcus sciuri sp. nov. and Its Subspecies.
  • Webster1994 - Identification of the Staphylococcus sciuri Species Group with Eco RI Fragments Containing rRNA Sequences and Description of Staphylococcus vitulus sp. nov.
  • Schleifer2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Staphylococcaceae, Genus I. Staphylococcus
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MAMMALIICOCCUS SCIURI
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Li2019b - Disordered intestinal microbes are associated with the activity of Systemic Lupus Erythematosus
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • ...............................
    • GENERAL REFERENCES FOR MAMMALIICOCCUS SCIURI
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021