Massilia haematophila

(aka Naxibacter haematophilus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Massilia haematophila, (aka Naxibacter haematophilus), is a Gram-negative, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Massilia haematophila is probably a rare gut coloniser. (Kampfer2011; Kampfer2008)



  • This organism has been recovered from human faeces and clinical sources (blood - CCUG). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Is a rare opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Kampfer2011); (Kampfer2008);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 5.5; tolerates pH 10.5;
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 37℃; Grows optimally at 25-30℃.
  • ⥅
  • Substrates assimilated or utilised:
  • glycogen; maltose; acetate; adipate; fumarate; 3-hydroxybenzoate; 4-hydroxybenzoate; malate; propionate; pyruvate; suberate; valerate; oxoglutarate;
  • Active enzymes:
  • alkaline phosphatase; oxidase;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • ONPG test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Kampfer2008);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; penicillin G;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • trimethoprim;
  • Miscellaneous antibiotics:
  • colistin; polymyxin B;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Burkholderiales Family:  Oxalobacteraceae Genus:  Massilia Alt. name:  Naxibacter haematophilus Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and clinical sources (blood - CCUG)
    Opt. T:  25-30℃
    Low T(℃):  15(+)
    Mid T(℃):  37(+)
    pH 4.2-5.9:  5.5(+)
    pH >8:  10.5(+)
    		Aesculin:  neg Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  neg Cellubiose:  neg Maltose:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Maltose:  + Sucrose:  neg Trehalose:  neg Gluconate:  neg Glycogen:  + Mannitol:  neg Ala:  neg His:  neg Pro:  neg Ser:  neg Acetate:  + Aconitate:  cis(neg) Adipate:  + Citrate:  neg Fumarate:  + 3-Hydroxybutyrate:  neg 3-Hydroxybenzoate:  + 4-Hydroxybenzoate:  + Lactate:  neg Malate:  + Propionate:  + Pyruvate:  + Suberate:  + Valerate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Urease:  neg β-Galactosidase:  neg AlkalineP:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(25; disc)
    Augmentin:  S(30; disc)
    penicillin_G:  S(10U)
    gentamicin:  S(10; disc)
    ciprofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    rifampicin:  S(5; disc)
    trimethoprim:  S(5; disc)
    colistin:  S(25; disc)
    polymyxin_B:  S(300U)

    References

    SPECIFIC REFERENCES FOR MASSILIA HAEMATOPHILA
  • Kampfer2011 - Revision of the genus Massilia La Scola et al. 2000, with an emended description of the genus and inclusion of all species of the genus Naxibacter as new combinations, and proposal of Massilia consociata sp. nov.
  • Kampfer2008 - Naxibacter varians sp. nov. and Naxibacter haematophilus sp. nov., and emended description of the genus Naxibacter.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MASSILIA HAEMATOPHILA
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
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    • Added: December 15, 2021