Massilioclostridium coli

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Massilioclostridium coli is a Gram-negative, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 40.0%. Massilioclostridium coli is a common gut coloniser. (Lo2017)



  • This organism has been recovered from human left colon (Lo2017). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 98% of Europeans (unseenbio.com).
    • GENERAL CHARACTERISTICS (Lo2017);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 5.0; tolerates pH 8.0; Grows optimally at pH 7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-tagatose; 5-ketogluconate;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; esterase C4; naphthol-ASBI-P;
    • SPECIAL FEATURES (Lo2017);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Lo2017);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; imipenem;
  • oxacillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Aminoglycosides:
  • tobramycin;
  • gentamicin;
  • Heterocycles:
  • metronidazole;
  • fosfomycin; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • daptomycin;
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Massilioclostridium Gram stain:  neg O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human left colon (Lo2017)
    DNA G+C(%):  40.0
    Opt. T:  37℃
    High T(℃):  45(+)
    NaCl 0.5-2%:  0(+)
    Opt. pH:  7.0
    pH 4.2-5.9:  5.0(+)
    pH 6.0-8.0:  8.0(+)
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  neg Galactose:  neg Glucose:  neg Mannose:  neg Ribose:  neg D-Tagatose:  + Maltose:  neg Sucrose:  neg Aesculin:  neg Arbutin:  neg 5-Ketogluconate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg β-Galactosidase:  neg β-Glucosidase:  neg Trypsin:  neg CystineAA:  neg LeuAA:  neg AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  Sens
    oxacillin:  Res
    imipenem:  Sens
    gentamicin:  Res
    tobramycin:  Sens
    erythromycin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Res
    vancomycin:  Sens
    fosfomycin:  Res
    metronidazole:  Sens
    SXT:  Res
    daptomycin:  Sens
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR MASSILIOCLOSTRIDIUM COLI
  • Lo2017 - Massilioclostridium coli gen. nov., sp. nov., a new member of the Clostridiaceae family isolated from the left colon of a 27-year-old woman.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MASSILIOCLOSTRIDIUM COLI
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 07, 2022