Mediterranea massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Mediterranea massiliensis is a Gram-negative, non-spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 51.7%. Mediterranea massiliensis is probably a rare gut coloniser. (Mailhe2016d; Ngom2017)



  • This organism has been recovered from the colon of a patient. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Ngom2017);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 5; tolerates pH 8.0; Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • grows at 28℃; grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose; starch; 5-ketogluconate;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; fucosidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase;
    • SPECIAL FEATURES (Ngom2017);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Ngom2017);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem;
  • oxacillin; penicillin;
  • Cephalosporins:
  • cefotaxime;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Aminoglycosides:
  • gentamicin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • fosfomycin; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Bacteroidaceae Genus:  Mediterranea Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  the colon of a patient
    DNA G+C(%):  51.7
    Opt. T:  37℃
    Lower T(℃):  28(+)
    High T(℃):  45(+)
    NaCl 0.5-2%:  0(+)
    Opt. pH:  7
    pH 4.2-5.9:  5(+)
    pH 6.0-8.0:  8.0(+)
    		Aesculin:  neg Urea:  neg Gelatin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  neg Glucose:  + Mannose:  + Ribose:  neg Lactose:  neg Maltose:  neg Starch:  + 5-Ketogluconate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + α-Mannosidase:  neg Chymotrypsin:  neg Trypsin:  neg AlkalineP:  + AcidP:  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    oxacillin:  Res
    penicillin:  Res
    imipenem:  Sens
    cefotaxime:  Res
    gentamicin:  Res
    tobramycin:  Res
    erythromycin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Res
    vancomycin:  Res
    rifampicin:  Sens
    fosfomycin:  Res
    metronidazole:  Sens
    SXT:  Res
    clindamycin:  Res

    References

    SPECIFIC REFERENCES FOR MEDITERRANEA MASSILIENSIS
  • Mailhe2016d - 'Mediterranea massiliensis' gen. nov., sp. nov., a new human-associated bacterium isolated from the right and left colon lavage of a 58-year-old patient.
  • Ngom2017 - Noncontiguous finished genome sequence and description of Mediterranea massiliensis gen. nov., sp. nov., a new member of the Bacteroidaceae family isolated from human colon.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MEDITERRANEA MASSILIENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022