Megamonas rupellensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Megamonas rupellensis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 33%. Megamonas rupellensis is probably a rare gut coloniser. (Chevrot2008)



  • This organism has been recovered from human faeces and duck caecum. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Chevrot2008);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 5; tolerates pH 9; Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; glucose; mannose; xylose; cellubiose; lactose; maltose; raffinose; sucrose; trehalose; glycerol; mannitol; sorbitol; salicin;
    • SPECIAL FEATURES (Chevrot2008);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Nitrite:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Chevrot2008);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem;
  • Heterocycles:
  • chloramphenicol; metronidazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Selenomonadales Family:  Selenomonadaceae Genus:  Megamonas Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and duck caecum
    DNA G+C(%):  33
    Opt. T:  37℃
    Opt. pH:  7
    pH 4.2-5.9:  5(+)
    pH >8:  9(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  neg Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Sucrose:  + Trehalose:  + Glycerol:  + Mannitol:  + Sorbitol:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(25; disc)
    Augmentin:  S(30; disc)
    imipenem:  S(10; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  R(30; disc)
    chloramphenicol:  S(30; disc)
    metronidazole:  S(4; disc)

    References

    SPECIFIC REFERENCES FOR MEGAMONAS RUPELLENSIS
  • Chevrot2008 - Megamonas rupellensis sp. nov., an anaerobe isolated from the caecum of a duck.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Huang2019a - Metagenome-wide association study of the alterations in the intestinal microbiome composition of ankylosing spondylitis patients and the effect of traditional and herbal treatment
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MEGAMONAS RUPELLENSIS
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
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    • Added: December 15, 2021