Megasphaera cerevisiae

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Megasphaera cerevisiae is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 42.4-44.8%. Megasphaera cerevisiae is probably a rare gut coloniser.



  • This organism has been recovered from spoiled bottled beer. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 37℃; doesn't grow at 41℃; Grows optimally at 28℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; pyruvate;
  • ±
  • Strain-dependent acid from carbs:
  • arabinose;
  • ⥅
  • Substrates assimilated or utilised:
  • lactate; pyruvate;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (minor); propionate (minor); butyrate; valerate (minor); isobutyrate (minor); isovalerate; H₂S; caproateminor; CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • NO3➔NO2:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Veillonellales Family:  Veillonellaceae Genus:  Megasphaera Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  spoiled bottled beer
    DNA G+C(%):  42.4-44.8
    Opt. T:  28℃
    Low T(℃):  15(+)
    Mid T(℃):  37(+)
    High T(℃):  41(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  d Fructose:  + Glucose:  neg Mannose:  neg Ribose:  neg Xylose:  neg Cellubiose:  neg Maltose:  neg Trehalose:  neg Glycerol:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Glucose:  neg Lactate:  + Pyruvate:  + Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  minor(+) Propionate:  minor(+) Butyrate:  + Valerate:  minor(+) Isobutyrate:  minor(+) Isovalerate:  + H2S:  + Caproate:  minor CO2:  + H2:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR MEGASPHAERA CEREVISIAE
  • Engelmann1985 - Megasphaera cerevisiae sp. nov.: A New Gram-negative Obligately Anaerobic Coccus Isolated from Spoiled Beer.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MEGASPHAERA CEREVISIAE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • ...............................
    • Added: May 15, 2022