Megasphaera stantonii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Megasphaera stantonii is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 52.1%. Megasphaera stantonii is probably a rare gut coloniser. (Maki2018)



  • This organism has been recovered from chicken caeca. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Maki2018);
    Character Response
  • 💧
  • Bile tolerance:
  • Doesn't tolerate bile
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 50℃; Grows optimally at 42℃.
  • ⥅
  • Substrates assimilated or utilised:
  • fructose; gluconate; ribose; alanine; arginine; glycine; isoleucine; lysine; phenylalanine; proline; serine; tryptophan; tyrosine; pyruvate; succinate;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; propionate (minor); butyrate; lactate (minor); isovalerate;
    • RESPONSE TO ANTIBIOTICS (Maki2018);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Aminoglycosides:
  • streptomycin;
  • Polypep/ketides:
  • bacitracin;
  • Heterocycles:
  • chloramphenicol;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • lincomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Veillonellales Family:  Veillonellaceae Genus:  Megasphaera Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  chicken caeca
    DNA G+C(%):  52.1
    Opt. T:  42℃
    Lower T(℃):  30(+)
    High T(℃):  50(+)
    Bile reaction(%):  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  neg Mannose:  neg Ribose:  + Maltose:  neg Gluconate:  + Mannitol:  neg Ala:  + Arg:  + Gly:  + Ile:  + Lys:  + Phe:  + Pro:  + Ser:  + Trp:  + Tyr:  + DL-Lactate:  neg Pyruvate:  + Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  Sens
    streptomycin:  Res
    erythromycin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Res
    vancomycin:  Res
    bacitracin:  Sens
    chloramphenicol:  Sens
    lincomycin:  Sens

    References

    SPECIFIC REFERENCES FOR MEGASPHAERA STANTONII
  • Maki2018 - Megasphaera stantonii sp. nov., a butyrate-producing bacterium isolated from the cecum of a healthy chicken.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MEGASPHAERA STANTONII
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022