Methanobrevibacter millerae

Archaea
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Methanobrevibacter millerae is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 31-32%. Methanobrevibacter millerae is probably a rare gut coloniser. (Rea2007)



  • This organism has been recovered from ovine and bovine rumen. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Uses H2/CO2 or formate to produce methane. Requires acetate and yeast extract components for growth.
    • GENERAL CHARACTERISTICS (Rea2007);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 2.6% salt;
  • 💧
  • Bile tolerance:
  • Sensitive
  • pH
  • Acidity tolerance:
  • tolerates pH 5.5; tolerates pH 10; Grows optimally at pH 7.0-8.0.
  • 🌡
  • Temperature tolerance:
  • grows at 33℃; grows at 43℃; Grows optimally at 36-42℃.
  • ⥅
  • Substrates assimilated or utilised:
  • formate;
    • SPECIAL FEATURES (Rea2007);
    Character Response

    Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Euryarchaeota Class:  Methanobacteria Order:  Methanobacteriales Family:  Methanobacteriaceae Genus:  Methanobrevibacter Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  ovine and bovine rumen
    DNA G+C(%):  31-32
    Opt. T:  36-42℃
    Mid T(℃):  33(+)
    High T(℃):  43(+)
    NaCl 3-5%:  2.6(+)
    Opt. pH:  7.0-8.0
    pH 4.2-5.9:  5.5(+)
    pH >8:  10(+)
    Bile reaction(%):  S
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Ethanol:  neg Methanol:  neg Acetate:  neg Formate:  +

    References

    SPECIFIC REFERENCES FOR METHANOBREVIBACTER MILLERAE
  • Rea2007 - Methanobrevibacter millerae sp. nov. and Methanobrevibacter olleyae sp. nov., methanogens from the ovine and bovine rumen that can utilize formate for growth.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR METHANOBREVIBACTER MILLERAE
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022