Methanobrevibacter oralis

Archaea
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Methanobrevibacter oralis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 28%. Methanobrevibacter oralis is probably a rare gut coloniser. (Ferrari1994)



  • This organism has been recovered from subgingival dental plaque. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Requires H2/CO2 and produces methane. Fecal extract (with VFA) was required for growth.
    • GENERAL CHARACTERISTICS (Ferrari1994);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 0.5% salt;
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 5.9; doesn't tolerate pH 8.1; Grows optimally at pH 6.9-7.4.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 36-38℃.
    • SPECIAL FEATURES (Ferrari1994);
    Character Response

    Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Euryarchaeota Class:  Methanobacteria Order:  Methanobacteriales Family:  Methanobacteriaceae Genus:  Methanobrevibacter Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  subgingival dental plaque
    DNA G+C(%):  28
    Opt. T:  36-38℃
    NaCl 0.5-2%:  0.5(+)
    Opt. pH:  6.9-7.4
    pH 4.2-5.9:  5.9(neg)
    pH >8:  8.1(neg)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Methanol:  neg Acetate:  neg Formate:  neg

    References

    SPECIFIC REFERENCES FOR METHANOBREVIBACTER ORALIS
  • Ferrari1994 - Isolation and characterization of Methanobrevibacter oralis sp. nov.
  • Poehlein2016 - Draft Genome Sequences of Methanobrevibacter curvatus DSM11111, Methanobrevibacter cuticularis DSM11139, Methanobrevibacter filiformis DSM11501, and Methanobrevibacter oralis DSM7256.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR METHANOBREVIBACTER ORALIS
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022