Methanomassiliicoccus intestinalis

Archaea
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Methanomassiliicoccus intestinalis is a Gram-positive, non-spore-forming, strictly anaerobic, coccus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 41.3%. Methanomassiliicoccus intestinalis is probably a rare gut coloniser. (Borrel2013)



  • This organism has been recovered from human faeces (Borrel2013). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS
    Character Response

  • N/A

  • The characterization of these methanogens led us to propose that human-associated Archaea might even have unexpected positive effects on health. Specifically, these species have the genetic potential to deplete a deleterious compound, trimethylamine (TMA), through methanogenesis based on the H2-dependent reduction of methyl compounds. [PMID: 28585938] About one-third of the adult human population excretes methane through pulmonary respiration [PMID: 5111441]; that methane is produced by bacteria in the gut. Most methane is expelled from the body in flatus. Indeed, all healthy humans appear to produce methane but only in a subset of patients is that methane absorbed into the blood and excreted via the lungs [PMID: 3965369].

  • GutFeeling KnowledgeBase COMMENTS [Website]

    This organism is a methanogenic archaeon isolated from human feces. [PMID: 23846268]

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Euryarchaeota Class:  Thermoplasmata Order:  Methanomassiliicoccales Family:  Methanomassiliicoccaceae Genus:  Methanomassiliicoccus Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Morphology:  Coccus
    Health:  Unknown
    Source:  human faeces (Borrel2013)
    DNA G+C(%):  41.3

    References

    SPECIFIC REFERENCES FOR METHANOMASSILIICOCCUS INTESTINALIS
  • Borrel2013 - Genome Sequence of 'Candidatus Methanomassiliicoccus intestinalis' Issoire-Mx1, a Third Thermoplasmatales -Related Methanogenic Archaeon from Human Feces.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR METHANOMASSILIICOCCUS INTESTINALIS
  • King2019 - Baseline human gut microbiota profile in healthy people and standard reporting template.
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    • Added: February 08, 2021