Methanosphaera stadtmanae

(aka Methanosphaera stadtmaniae)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Methanosphaera stadtmanae, (aka Methanosphaera stadtmaniae), is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 10 gut microbiome compilation studies or metastudies. The DNA G+C content is 25.8%. Methanosphaera stadtmanae is probably a common, although minor, coloniser of the gut. (Miller1985)



  • This organism has been recovered from human large intestine (Miller1985). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Miller1985);
    Character Response
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 6.5-6.9.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 25℃; doesn't grow at 45℃; Grows optimally at 36-40℃.
  • ⥅
  • Substrates assimilated or utilised:
  • methanol; isoleucine; leucine; acetate;
    • SPECIAL FEATURES (Miller1985);
    Character Response
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Sulfate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Euryarchaeota Class:  Methanobacteria Order:  Methanobacteriales Family:  Methanobacteriaceae Genus:  Methanosphaera Alt. name:  Methanosphaera stadtmaniae Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  human large intestine (Miller1985)
    DNA G+C(%):  25.8
    Opt. T:  36-40℃
    Lower T(℃):  25(neg)
    High T(℃):  45(neg)
    Opt. pH:  6.5-6.9
    Bile reaction(%):  20(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Methanol:  + Ile:  + Leu:  + Acetate:  +

    References

    SPECIFIC REFERENCES FOR METHANOSPHAERA STADTMANAE
  • Miller1985 - Methanosphaera stadtmaniae gen. nov., sp. nov.: a species that forms methane by reducing methanol with hydrogen.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR METHANOSPHAERA STADTMANAE
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Karlsson2013 - Gut metagenome in European women with normal, impaired and diabetic glucose control
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Nam2008a - Bacterial, archaeal, and eukaryal diversity in the intestines of Korean people.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: July 12, 2021