Methylobacterium adhaesivum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Methylobacterium adhaesivum is a Gram-negative, non-spore-forming, aerobic, motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 63.6%. Methylobacterium adhaesivum is likely to be transient and not a long-term gut coloniser. (Gallego2006a)



  • This organism has been recovered from human faeces, and drinking water. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Borderline cold mesophile, with optimum growth temp of 28C. Unlikely gut coloniser.
    • GENERAL CHARACTERISTICS (Gallego2006a);
    Character Response
  • Substrates hydrolysed or digested:
  • urea;
  • 🧂
  • Salt tolerance:
  • tolerates 0.9% salt; doesn't tolerate 3-5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 5.0; tolerates pH 6.0-8.0; tolerates pH 9; Grows optimally at pH 6.5.
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 35℃; Grows optimally at 28℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; fructose; galactose; glucose; mannose; maltose;
  • ⥅
  • Substrates assimilated or utilised:
  • fructose; glycerol; methanol; aspartate; glutamate; acetate; citrate; formate; 3-hydroxybutyrate; 2-ketoglutarate; L-malate; propionate; pyruvate; succinate; glutamine; 2-hydroxybutyrate; 4-hydroxybutyrate; methyl succinate; succinamate; methyl pyruvate; D-malate; L-lactate;
  • Active enzymes:
  • catalase; urease;
    • SPECIAL FEATURES (Gallego2006a);
    Character Response
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✗
  • Methyl red test:
  • not active
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
  • Pigments:
  • pink

  • McLaughlin, S. D., Walker, A. W., Churcher, C., Clark, S. K., Tekkis, P. P., Johnson, M. W., Parkhill, J., Ciclitira, P. J., Dougan, G., Nicholls, R. J., & Petrovska, L. (2010). The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing. Annals of Surgery, 252(1), 90–98.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Alphaproteobacteria Order:  Hyphomicrobiales Family:  Methylobacteriaceae Genus:  Methylobacterium Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Swimming Morphology:  Rod Pigment:  pink
    Health:  Unknown
    Source:  human faeces, and drinking water
    DNA G+C(%):  63.6
    Opt. T:  28℃
    Low T(℃):  15(+)
    Mid T(℃):  35(+)
    NaCl 0.5-2%:  0.9(+)
    NaCl 3-5%:  3-5(neg)
    Opt. pH:  6.5
    pH 4.2-5.9:  5.0(+)
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  9(+)
    		Urea:  + Gelatin:  neg Starch:  neg Casein:  neg DNA:  neg Tween:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Mannose:  + Maltose:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  + Mannose:  neg Rhamnose:  neg Ribose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Maltotriose:  neg Raffinose:  neg Sucrose:  neg D-Turanose:  neg Trehalose:  neg N_Acetyl_glucosamine:  neg Amygdalin:  neg D-Arabitol:  neg Arbutin:  neg Dextrin:  neg Gluconate:  neg Glycerol:  + Glycogen:  neg Inositol:  neg Inulin:  neg Mannitol:  neg Me-α-D-Glc:  neg Methanol:  + Salicin:  neg Sorbitol:  neg Xylitol:  neg Ala:  neg D-Ala:  neg Asp:  + Glu:  + Ser:  neg Acetate:  + Citrate:  + Formate:  + 3-Hydroxybutyrate:  + L-Malate:  + Propionate:  + Pyruvate:  + Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  w Catalase:  + Urease:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg Pigment:  pink

    References

    SPECIFIC REFERENCES FOR METHYLOBACTERIUM ADHAESIVUM
  • Gallego2006a - Methylobacterium adhaesivum sp. nov., a methylotrophic bacterium isolated from drinking water.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR METHYLOBACTERIUM ADHAESIVUM
  • McLaughlin2010 - The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
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    • Added: April 08, 2021