Microvirga massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Microvirga massiliensis is a Gram-negative, non-spore-forming, aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 63%. Microvirga massiliensis is probably a rare gut coloniser. (Caputo2016)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Caputo2016);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • trehalose;
  • ⥅
  • Substrates assimilated or utilised:
  • ethanol; acetate; propionate; succinate;
  • Active enzymes:
  • acid phosphatase; catalase; cystine arylamidase; esterase C4; esterase lipase C8; Leu arylamidase; trypsin; naphthol-ASBI-P;
    • SPECIAL FEATURES (Caputo2016);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Caputo2016);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem; penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • nitrofurantoin;
  • Vancomycins:
  • vancomycin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Alphaproteobacteria Order:  Hyphomicrobiales Family:  Methylobacteriaceae Genus:  Microvirga Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:   Positive
    Source:  human faeces
    DNA G+C(%):  63
    		Aesculin:  neg Urea:  neg Gelatin:  neg Arginine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  + Turanose:  neg Amygdalin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Glucose:  neg Mannose:  neg Maltose:  neg N_Acetyl_glucosamine:  neg Ethanol:  + Gluconate:  neg Mannitol:  neg Acetate:  + Adipate:  neg Caprate:  neg Citrate:  neg Malate:  neg Phenylacetate:  neg Propionate:  + Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  neg Trypsin:  + CystineAA:  + LeuAA:  + ValAA:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(25; disc)
    Augmentin:  S(30)
    penicillin:  S(10; disc)
    imipenem:  S(10; disc)
    amikacin:  S(30; disc)
    gentamicin:  S(15; disc)
    tobramycin:  S(10; disc)
    erythromycin:  S(15; disc)
    ciprofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(30; disc)
    vancomycin:  R(30; disc)
    rifampicin:  S(30; disc)
    metronidazole:  S(4; disc)
    nitrofurantoin:  R(300; disc)

    References

    SPECIFIC REFERENCES FOR MICROVIRGA MASSILIENSIS
  • Caputo2016 - Microvirga massiliensis sp. nov., the human commensal with the largest genome.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MICROVIRGA MASSILIENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • Added: April 08, 2021