Mitsuokella jalaludinii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Mitsuokella jalaludinii is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 6 gut microbiome compilation studies or metastudies. The DNA G+C content is 56.9%. Mitsuokella jalaludinii is probably a common, although minor, coloniser of the gut. (Lan2002; Willems2011bBergey)



  • This organism has been recovered from human faeces, and bovine rumen. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 16% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Lan2002); (Willems2011bBergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; starch;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 4.5% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 20℃; grows at 47℃; Grows optimally at 42℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; glucose; mannose; ribose; xylose; aesculin; starch; cellubiose; lactose; maltose; melibiose; raffinose; sucrose; trehalose; D-turanose; D-arabitol; glycerol; inositol; sorbitol; arbutin; 5-ketogluconate; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • melibiose;
    • SPECIAL FEATURES (Lan2002); (Willems2011bBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate; succinate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✓
  • Methyl red test:
  • active
  • ✓
  • VP test:
  • active
  • ✓
  • Nitrate:
  • reduced
  • ✓
  • NO3➔NO2:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Lan2002); (Willems2011bBergey);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Macrolides:
  • erythromycin;
  • Aminoglycosides:
  • kanamycin; neomycin;
  • Polypep/ketides:
  • bacitracin;

  • Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006). Microbial ecology: human gut microbes associated with obesity. Nature, 444(7122), 1022–1023.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Selenomonadales Family:  Selenomonadaceae Genus:  Mitsuokella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, and bovine rumen
    DNA G+C(%):  56.9
    Opt. T:  42℃
    Lower T(℃):  20(neg)
    High T(℃):  47(+)
    NaCl 3-5%:  4.5(neg)
    		Aesculin:  + Gelatin:  neg Starch:  + Tween:  80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  + Sorbose:  neg L-Sorbose:  neg D-Tagatose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  neg Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  + Amygdalin:  neg Aesculin:  + Glycogen:  neg Inulin:  neg Starch:  + Adonitol:  neg D-Arabitol:  + L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  + Inositol:  + Mannitol:  neg Sorbitol:  + Xylitol:  neg Arbutin:  + Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  + Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg ArgDC:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Lactate:  + Succinate:  + H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  R(10; disc)
    kanamycin:  R(100; disc)
    neomycin:  R(25; disc)
    erythromycin:  R(50; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    bacitracin:  R(3U)

    References

    SPECIFIC REFERENCES FOR MITSUOKELLA JALALUDINII
  • Lan2002 - Mitsuokella jalaludinii sp. nov., from the rumens of cattle in Malaysia.
  • Willems2011bBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Veillonellaceae, Genus XIV. Mitsuokella
  • Lozupone2013 - Alterations in the gut microbiota associated with HIV-1 infection
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MITSUOKELLA JALALUDINII
  • Browne2016 - Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation.
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR MITSUOKELLA JALALUDINII
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021