Moellerella wisconsensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Moellerella wisconsensis is a Gram-negative, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. Moellerella wisconsensis is probably a rare gut coloniser. (Farmer1985; HickmanBrenner1984; Farmer2005dBergey)



  • This organism has been recovered from human faeces and clinical sources (wound, sputum, peritoneum exsudate - CCUG). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Farmer1985); (HickmanBrenner1984); (Farmer2005dBergey);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; galactose; glucose; mannose; lactose; melibiose; raffinose; sucrose; adonitol; D-arabitol;
  • ⥅
  • Substrates assimilated or utilised:
  • citrate;
  • Active enzymes:
  • α-galactosidase; β-galactosidase; β-glucosidase;
    • SPECIAL FEATURES (Farmer1985); (HickmanBrenner1984); (Farmer2005dBergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✓
  • Methyl red test:
  • active
  • ✗
  • VP test:
  • not active
  • ✓
  • ONPG test:
  • active
  • ±
  • KCN growth:
  • strain-dependent
  • ±
  • NO3➔NO2:
  • reduced by most strains
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (HickmanBrenner1984); (Farmer2005dBergey);
    Class Active Resistant
  • Penicillins:
  • ampicillin; carbenicillin; penicillin;
  • Cephalosporins:
  • cephalothin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; kanamycin; streptomycin;
  • Heterocycles:
  • chloramphenicol;
  • sulfadiazine;
  • Miscellaneous antibiotics:
  • colistin;

  • Hickman-Brenner, F. W., Huntley-Carter, G. P., Saitoh, Y., Steigerwalt, A. G., Farmer, J. J., 3rd, & Brenner, D. J. (1984). Moellerella wisconsensis, a new genus and species of Enterobacteriaceae found in human stool specimens. Journal of Clinical Microbiology, 19(4), 460–463.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Enterobacterales Family:  Enterobacteriaceae Genus:  Moellerella Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces and clinical sources (wound, sputum, peritoneum exsudate - CCUG)
    		Aesculin:  neg Urea:  neg Gelatin:  neg DNA:  neg Tyrosine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + L-Arabinose:  neg Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  + Maltose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Adonitol:  + D-Arabitol:  + L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  w Inositol:  neg Mannitol:  w Sorbitol:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Acetate:  neg Citrate:  + Malonate:  neg Mucate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  + β-Glucuronidase:  neg ArgDH:  neg ArgDC:  neg LysDC:  neg OrnDC:  neg Phe deaminase:  neg DNAse:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  R(10; disc, variable)
    carbenicil:  R(100; disc, variable)
    penicillin:  R(10U)
    cephalothin:  S(10; disc)
    gentamicin:  S(10; disc)
    kanamycin:  S(30; disc, variable)
    streptomycin:  S(10; disc, variable)
    nalidixic-acid:  S(30; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(30; disc, variable)
    chloramphenicol:  S(30; disc)
    sulfadiazine:  R(250; disc, variable)
    colistin:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR MOELLERELLA WISCONSENSIS
  • Farmer1985 - Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens.
  • HickmanBrenner1984 - Moellerella wisconsensis, a new genus and species of Enterobacteriaceae found in human stool specimens.
  • Farmer2005dBergey - Bergey's manual of systematic bacteriology. Vol. 2, The Gammaproteobacteria Part B. Family Enterobacteriaceae, Genus XX. Moellerella
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MOELLERELLA WISCONSENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR MOELLERELLA WISCONSENSIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021