Murdochiella massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Murdochiella massiliensis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 48.9%. Murdochiella massiliensis is probably a rare gut coloniser. (Vicino2016)



  • This organism has been recovered from the faeces of a healthy child from Senegal. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Vicino2016);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 42℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; ribose; glycerol; mannitol; 5-ketogluconate; N-Ac glucosamine;
  • Active enzymes:
  • acid phosphatase; N-Ac β-glucosaminidase; esterase lipase C8; β-galactosidase; β-glucuronidase; Leu arylamidase; α-mannosidase;
    • RESPONSE TO ANTIBIOTICS (Vicino2016);
    Class Active Resistant
  • Penicillins:
  • aztreonam; imipenem;
  • Cephalosporins:
  • ceftazidime;
  • Macrolides:
  • erythromycin;
  • Quinolines:
  • ciprofloxacin;
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin;
  • tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;
  • fosfomycin;
  • Vancomycins:
  • teicoplanin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Tissierellia Order:  Tissierellales Family:  Peptoniphilaceae Genus:  Murdochiella Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  the faeces of a healthy child from Senegal
    DNA G+C(%):  48.9
    Lower T(℃):  25(+)
    High T(℃):  42(+)
    NaCl 3-5%:  5(+)
    pH 6.0-8.0:  6.0(+)
    pH >8:  8.5(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  + Galactose:  + Glucose:  + Mannose:  + Ribose:  + Glycerol:  + Mannitol:  + 5-Ketogluconate:  + NAc-α-GA:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Ac-β-glcamnd:  + β-Galactosidase:  + β-Glucuronidase:  + α-Mannosidase:  + LeuAA:  + AcidP:  + Esterase(C4):  neg EstLip(C8):  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    aztreonam:  Sens
    imipenem:  Sens
    ceftazidime:  Sens
    gentamicin:  Sens
    tobramycin:  Res
    erythromycin:  Sens
    ciprofloxacin:  Sens
    nalidixic-acid:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    teicoplanin:  Sens
    rifampicin:  Sens
    fosfomycin:  Res
    SXT:  Sens
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR MURDOCHIELLA MASSILIENSIS
  • Vicino2016 - Non contiguous-finished genome sequence and description of Murdochiella massiliensis strain SIT12 sp. nov.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MURDOCHIELLA MASSILIENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022