Muribaculum intestinale

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Muribaculum intestinale is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 49.9%. Muribaculum intestinale is probably a common, although minor, coloniser of the gut. (Lagkouvardos2016; Lagkouvardos2019)



  • This organism has been recovered from the intestines of mice. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • In 31% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Lagkouvardos2016); (Lagkouvardos2019);
    Character Response
  • Substrates hydrolysed or digested:
  • pectin;
  • ⥅
  • Substrates assimilated or utilised:
  • galactose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; N-Ac β-glucosaminidase; α-galactosidase; β-galactosidase; Leu-Gly arylamidase;
    • SPECIAL FEATURES (Lagkouvardos2016);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Muribaculaceae Genus:  Muribaculum Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  the intestines of mice
    DNA G+C(%):  49.9
    		Aesculin:  neg Urea:  neg Gelatin:  neg Pectin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  neg Mannose:  neg Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Sucrose:  neg Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Galactose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Ac-β-glcamnd:  + α-Galactosidase:  + β-Galactosidase:  + β-Glucosidase:  neg AlanineAA:  + LeuGlyAA:  + AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg

    References

    SPECIFIC REFERENCES FOR MURIBACULUM INTESTINALE
  • Lagkouvardos2016 - The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.
  • Lagkouvardos2019 - Sequence and cultivation study of Muribaculaceae reveals novel species, host preference, and functional potential of this yet undescribed family.
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Ciocan2018 - Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MURIBACULUM INTESTINALE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022