General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview


  • Mycobacterium kansasii is a Gram-variable, non-spore-forming, aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. Mycobacterium kansasii is likely to be transient and not a long-term gut coloniser. (Magee2012Bergey)



  • This organism has been recovered from pulmonary legions. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). Is a known human pathogen. A possible gut commensal.

  • QUIRKS
  • Pathogenic; unlikely to be a coloniser in a healthy microbiome.

  • GENERAL CHARACTERISTICS (Magee2012Bergey);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 32℃; grows at 42℃;
  • Active enzymes:
  • catalase;

  • SPECIAL FEATURES
    Character Response
  • Pigments:
  • bright yellow

  • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Tetracyclines:
  • doxycycline; minocycline; tetracycline; tigecycline;

  • Details


    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Mycobacteriales Family:  Mycobacteriaceae Genus:  Mycobacterium Gram stain:  vr O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  bright yellow
    Health:  Unknown
    Source:  pulmonary legions
    Mid T(℃):  32(+)
    High T(℃):  42(+)

    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  +

    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    Pigment:  bright yellow

    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  R(MIC50): 16, MIC90: 16, RNG: (4-32)
    minocycline:  R(MIC50): 8, MIC90: 8, RNG: (2-8)
    tetracycline:  R(MIC50): 32, MIC90: 128, RNG: (16-128)
    tigecycline:  R(MIC50): 16, MIC90: 32, RNG: (8-32)

    References


    SPECIFIC REFERENCES FOR MYCOBACTERIUM KANSASII
  • Nouioui2018 - Genome-Based Taxonomic Classification of the Phylum Actinobacteria.
  • Magee2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Mycobacteriaceae, Genus I. Bifidobacterium
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  • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MYCOBACTERIUM KANSASII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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