Mycobacterium simiae

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Mycobacterium simiae is a Gram-variable, non-spore-forming, aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Mycobacterium simiae is probably a rare gut coloniser. (Meissner1975; Magee2012Bergey)



  • This organism has been recovered from healthy monkeys and clinical sources (pulmonary disease). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Meissner1975); (Magee2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • urea;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 5% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • Active enzymes:
  • catalase; urease;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Nitrate:
  • not reduced
  • ✓
  • Pigments:
  • produced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Macrolides:
  • azithromycin;
  • Aminoglycosides:
  • streptomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Mycobacteriales Family:  Mycobacteriaceae Genus:  Mycobacterium Gram stain:  vr O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  +
    Health:  Unknown
    Source:  healthy monkeys and clinical sources (pulmonary disease)
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  45(neg)
    NaCl 3-5%:  5(neg)
    		Urea:  + Tween:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    streptomycin:  Res
    azithromycin:  S(4)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)

    References

    SPECIFIC REFERENCES FOR MYCOBACTERIUM SIMIAE
  • Nouioui2018 - Genome-Based Taxonomic Classification of the Phylum Actinobacteria.
  • Meissner1975 - Relationship between Mycobacterium simiae and Mycobacterium habana.
  • Baess1982 - Classification of Mycobacterium simiae by means of comparative reciprocal intradermal sensitin testing on guinea-pigs and deoxyribonucleic acid hybridization.
  • Magee2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Mycobacteriaceae, Genus I. Bifidobacterium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MYCOBACTERIUM SIMIAE
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022