Mycobacterium tuberculosis variant africanum

(aka Mycobacterium africanum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Mycobacterium tuberculosis variant africanum, (aka Mycobacterium africanum), is a Gram-variable, non-spore-forming, aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Mycobacterium tuberculosis variant africanum is unlikely to be a gut coloniser. (Magee2012Bergey)



  • This organism has been recovered from tuberculosis patients from Senegal. The risk classification (www.baua.de) for this organism is 3, i.e., high risk of individual infection, and some risk of spread (notes: vaccine available, zoonotic pathogen). This is a dangerous pathogen. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Magee2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • urea;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • Active enzymes:
  • acid phosphatase; urease;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Nitrate:
  • reduced
  • ✗
  • Pigments:
  • not produced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Mycobacteriales Family:  Mycobacteriaceae Genus:  Mycobacterium Alt. name:  Mycobacterium africanum Gram stain:  vr O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  tuberculosis patients from Senegal
    Opt. T:  37℃
    		Urea:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  + AcidP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  neg

    References

    SPECIFIC REFERENCES FOR MYCOBACTERIUM TUBERCULOSIS VARIANT AFRICANUM
  • Magee2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Mycobacteriaceae, Genus I. Bifidobacterium
  • Riojas2018 - Phylogenomic analysis of the species of the Mycobacterium tuberculosis complex demonstrates that Mycobacterium africanum, Mycobacterium bovis, Mycobacterium caprae, Mycobacterium microti and Mycobacterium pinnipedii are later heterotypic synonyms of Mycobacterium tuberculosis.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MYCOBACTERIUM TUBERCULOSIS VARIANT AFRICANUM
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022