Mycobacteroides abscessus subsp. bolletii

(aka Mycobacterium bolletii)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Mycobacteroides abscessus subsp. bolletii, (aka Mycobacterium bolletii), is a Gram-positive, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Mycobacteroides abscessus subsp. bolletii is likely to be transient and not a long-term gut coloniser. (Adekambi2006)



  • This organism has been recovered from sputum and stomach aspirate. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Is a known human pathogen. A possible gut commensal.
    • QUIRKS
  • Associated with chronic pneumonia. Multidrug-resistant species. Pathogenic; unlikely to be a coloniser in a healthy microbiome.
    • GENERAL CHARACTERISTICS (Adekambi2006);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 5% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 24℃; grows at 37℃; doesn't grow at 42℃; Grows optimally at 30℃.
    • SPECIAL FEATURES (Adekambi2006);
    Character Response
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Adekambi2006);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; imipenem; penicillin;
  • Cephalosporins:
  • cefotaxime; cefoxitin; cephalothin;
  • Macrolides:
  • azithromycin; clarithromycin; erythromycin;
  • Tetracyclines:
  • doxycycline; minocycline;
  • Quinolines:
  • ciprofloxacin; ofloxacin; pipemidic-acid; sparfloxacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin; teicoplanin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Mycobacteriales Family:  Mycobacteriaceae Genus:  Mycobacteroides Alt. name:  Mycobacterium bolletii Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  sputum and stomach aspirate
    Opt. T:  30℃
    Lower T(℃):  24(+)
    Mid T(℃):  37(+)
    High T(℃):  42(neg)
    NaCl 3-5%:  5(neg)
    		Urea:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Mannitol:  neg Sorbitol:  neg Citrate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  R(>256)
    Augmentin:  Var(MIC50): 30; disc), MIC90: Var(30; disc
    penicillin:  R(>32)
    imipenem:  R(>32)
    cefotaxime:  R(>256)
    cefoxitin:  R(30; disc)
    cephalothin:  R(30; disc)
    amikacin:  Var(MIC50): 24), MIC90: Var(24
    tobramycin:  Var(MIC50): 10; disc), MIC90: Var(10; disc
    azithromycin:  R(>256)
    erythromycin:  R(>256)
    clarithromycin:  R(>256)
    ciprofloxacin:  R(>32)
    ofloxacin:  R(>32)
    pipemidic_acid:  R(20; disc)
    sparfloxacin:  R(>32)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  R(>32)
    minocycline:  R(>256)
    teicoplanin:  R(>256)
    vancomycin:  R(>256)
    rifampicin:  R(>32)
    metronidazole:  R(>256)
    SXT:  Var(MIC50): 25; disc), MIC90: Var(25; disc
    colistin:  Var(MIC50): 50; disc), MIC90: Var(50; disc

    References

    SPECIFIC REFERENCES FOR MYCOBACTEROIDES ABSCESSUS SUBSP. BOLLETII
  • Tortoli2016 - Emended description of Mycobacterium abscessus, Mycobacterium abscessus subsp. abscessus and Mycobacterium abscessus subsp. bolletii and designation of Mycobacterium abscessus subsp. massiliense comb. nov.
  • Adekambi2006 - rpoB gene sequence-based characterization of emerging non-tuberculous mycobacteria with descriptions of Mycobacterium bolletii sp. nov., Mycobacterium phocaicum sp. nov. and Mycobacterium aubagnense sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR MYCOBACTEROIDES ABSCESSUS SUBSP. BOLLETII
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022