Mycolicibacterium cosmeticum

(aka Mycobacterium cosmeticum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Mycolicibacterium cosmeticum, (aka Mycobacterium cosmeticum), is a Gram-variable, non-spore-forming, aerobic, non-motile, rod-shaped bacterium. Mycolicibacterium cosmeticum is likely to be transient and not a long-term gut coloniser. (Cooksey2004)



  • This organism has been recovered from human faeces (18-yr-old - CCUG) and clinical sources. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Cooksey2004);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 5% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 45℃; Grows optimally at 35℃.
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; inositol; mannitol; trehalose; xylose; citrate;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Cooksey2004);
    Class Active Resistant
  • Penicillins:
  • imipenem;
  • Cephalosporins:
  • cefoxitin;
  • Macrolides:
  • clarithromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • amikacin; tobramycin;
  • Heterocycles:
  • sulfamethoxazole;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Mycobacteriaceae Genus:  Mycolicibacterium Alt. name:  Mycobacterium cosmeticum Gram stain:  vr O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (18-yr-old - CCUG) and clinical sources
    Opt. T:  35℃
    High T(℃):  45(neg)
    NaCl 3-5%:  5(neg)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  + Xylose:  + Trehalose:  + Inositol:  + Mannitol:  + Sorbitol:  neg Citrate:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    imipenem:  S(1)
    cefoxitin:  S(8)
    amikacin:  S(4)
    tobramycin:  S(4)
    clarithromycin:  S(0.25)
    ciprofloxacin:  S(0.25)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(0.25)
    sulfamethoxazole:  S(8)

    References

    SPECIFIC REFERENCES FOR MYCOLICIBACTERIUM COSMETICUM
  • Gupta2018 - Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera.
  • Cooksey2004 - Mycobacterium cosmeticum sp. nov., a novel rapidly growing species isolated from a cosmetic infection and from a nail salon.
  • ...............................
    • GENERAL REFERENCES FOR MYCOLICIBACTERIUM COSMETICUM
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: July 12, 2021