Negativicoccus succinicivorans

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Negativicoccus succinicivorans is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. Negativicoccus succinicivorans is probably a rare gut coloniser. (Marchandin2010)



  • This organism has been recovered from clinical sources (wound, blood - CCUG) and human faeces. Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Marchandin2010);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 37℃;
  • ⥅
  • Substrates assimilated or utilised:
  • succinate;
  • Active enzymes:
  • Arg arylamidase;
    • SPECIAL FEATURES (Marchandin2010);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; lactate (trace);
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Marchandin2010);
    Class Active Resistant
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • bile;
  • colistin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Veillonellales Family:  Veillonellaceae Genus:  Negativicoccus Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  clinical sources (wound, blood - CCUG) and human faeces
    Mid T(℃):  37(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    ArgAA:  + AlkalineP:  vr
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  S(500; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  R(5; disc)
    metronidazole:  S(50; disc)
    colistin:  R(10; disc)
    Bile:  S(1000; disc)

    References

    SPECIFIC REFERENCES FOR NEGATIVICOCCUS SUCCINICIVORANS
  • Marchandin2010 - Negativicoccus succinicivorans gen. nov., sp. nov., isolated from human clinical samples, emended description of the family Veillonellaceae and description of Negativicutes classis nov., Selenomonadales ord. nov. and Acidaminococcaceae fam. nov. in the bacterial phylum Firmicutes.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NEGATIVICOCCUS SUCCINICIVORANS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR NEGATIVICOCCUS SUCCINICIVORANS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021