Neisseria canis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Neisseria canis is a Gram-negative, non-spore-forming, aerobic, non-motile, diplococci bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 50%. Neisseria canis is probably a rare gut coloniser. (Tonjum2005Bergey)



  • This organism has been recovered from throats of cats and clinical sources (cat bite). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Tonjum2005Bergey);
    Character Response
  • ±
  • Strain-dependent hydrolysis or digestion:
  • DNA;
  • Active enzymes:
  • Ala arylamidase; carbonic anhydrase; catalase; Gly arylamidase; Leu arylamidase; oxidase; Pro arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • DNase; Ser arylamidase;
    • SPECIAL FEATURES (Tonjum2005Bergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • Haemolysis:
  • variable
  • ✓
  • Nitrate:
  • reduced
  • ✓
  • Nitrite:
  • reduced
  • Pigments:
  • yellow
    • RESPONSE TO ANTIBIOTICS (Goldstein1999a);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid;
  • Quinolines:
  • ciprofloxacin; gatifloxacin; levofloxacin; sparfloxacin; trovafloxacin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Neisseriales Family:  Neisseriaceae Genus:  Neisseria Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Diplococci Pigment:  yellow
    Health:  Unknown
    Source:  throats of cats and clinical sources (cat bite)
    DNA G+C(%):  50
    		Urea:  neg Gelatin:  neg Starch:  neg DNA:  d Hippurate:  neg Tween:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg L-Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Amygdalin:  neg Dextrin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg NAc-α-GA:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Carbonic anh.:  + α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  neg OrnDC:  neg Phe deaminase:  neg Trypsin:  neg AlanineAA:  + AlaPheProAA:  neg CystineAA:  neg GluGluAA:  neg GlyTrpAA:  neg GlyAA:  + HisAA:  neg LeuAA:  d(+) ProAA:  + PheAA:  neg PyrogluAA:  neg SerAA:  d TyrAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  neg DNAse:  d Esterase(C4):  neg EstLip(C8):  neg Lipase:  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg Pigment:  yellow
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  S(MIC50): 0.5, MIC90: 1, RNG: (0.125–1)
    ciprofloxacin:  S(MIC50): 0.008, MIC90: 0.125, RNG: (0.002–0.125)
    gatifloxacin:  S(MIC50): 0.008, MIC90: 0.06, RNG: (0.002–0.125)
    levofloxacin:  S(MIC50): 0.008, MIC90: 0.125, RNG: (0.004–0.125)
    sparfloxacin:  S(MIC50): 0.008, MIC90: 0.03, RNG: (0.004–0.125)
    trovafloxacin:  S(MIC50): 0.008, MIC90: 0.06, RNG: (0.002–0.06)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    colistin:  Sens

    References

    SPECIFIC REFERENCES FOR NEISSERIA CANIS
  • Tonjum2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Neisseriaceae, Genus I. Neisseria
  • Goldstein1999a - Activity of gatifloxacin compared to those of five other quinolones versus aerobic and anaerobic isolates from skin and soft tissue samples of human and animal bite wound infections.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NEISSERIA CANIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022