Neisseria macacae

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Neisseria macacae is a Gram-negative, non-spore-forming, aerobic, non-motile, diplococci bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 50–51%. Neisseria macacae is probably a rare gut coloniser. (Vedros1983; Tonjum2005Bergey)



  • This organism has been recovered from monkey isolates and human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Vedros1983); (Tonjum2005Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • DNA;
  • 🌡
  • Temperature tolerance:
  • grows weakly at 22℃; grows at 37℃; grows weakly at 42℃; Grows optimally at 35-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; maltose; sucrose;
  • Active enzymes:
  • Ala arylamidase; carbonic anhydrase; catalase; DNase; γ-Glu transferase; oxidase;
    • SPECIAL FEATURES (Vedros1983); (Tonjum2005Bergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • Haemolysis:
  • variable
  • ✗
  • Nitrate:
  • not reduced
  • ✓
  • Nitrite:
  • reduced
  • Pigments:
  • yellow

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Neisseriales Family:  Neisseriaceae Genus:  Neisseria Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Diplococci Pigment:  yellow
    Health:  Unknown
    Source:  monkey isolates and human faeces
    DNA G+C(%):  50–51
    Opt. T:  35-37℃
    Lower T(℃):  22(w)
    Mid T(℃):  37(+)
    High T(℃):  42(w)
    		Gelatin:  neg DNA:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg Galactose:  neg Glucose:  + Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg L-Sorbose:  neg D-Tagatose:  neg L-Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  neg Turanose:  neg Amygdalin:  neg Dextrin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg NAc-α-GA:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Carbonic anh.:  + α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  neg γ-Glu transf.:  + OrnDC:  neg AlanineAA:  + GlyTrpAA:  neg HisAA:  neg PyrogluAA:  neg ValAA:  neg AlkalineP:  neg DNAse:  + Esterase(C4):  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg Pigment:  yellow

    References

    SPECIFIC REFERENCES FOR NEISSERIA MACACAE
  • Vedros1983 - Neisseria macacae sp. nov., a new Neisseria Species Isolated from the Oropharynges of Rhesus Monkeys (Macaca mulatta).
  • Tonjum2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Neisseriaceae, Genus I. Neisseria
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NEISSERIA MACACAE
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: April 08, 2021