Neisseria oralis

(aka Neisseria mucosa subsp. heidelbergensis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Neisseria oralis, (aka Neisseria mucosa subsp. heidelbergensis), is a Gram-negative, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 52.6%. Neisseria oralis is probably a rare gut coloniser. (Wolfgang2013; Berger1971)



  • This organism has been recovered from human faeces, clinical sources (blood - CCUG) and healthy gingiva. Is a rare opportunistic pathogen. A possible gut commensal. Robust growth can have negative consequences for gut health.
    • GENERAL CHARACTERISTICS (Wolfgang2013); (Berger1971);
    Character Response
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 10℃; grows at 28℃; grows at 42℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; maltose;
  • ±
  • Strain-dependent acid from carbs:
  • lactose; sucrose;
  • Active enzymes:
  • carbonic anhydrase; catalase; γ-Glu transferase; oxidase; Pro arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • β-galactosidase;
    • SPECIAL FEATURES (Wolfgang2013); (Berger1971);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • Haemolysis:
  • alpha
  • ✓
  • NO3➔NO2:
  • reduced
  • Pigments:
  • yellow

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Neisseriales Family:  Neisseriaceae Genus:  Neisseria Alt. name:  Neisseria mucosa subsp. heidelbergensis Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus Pigment:  yellow
    Health:   Negative
    Source:  human faeces, clinical sources (blood - CCUG) and healthy gingiva
    DNA G+C(%):  52.6
    Low T(℃):  10(neg)
    Lower T(℃):  28(+)
    High T(℃):  42(+)
    		Aesculin:  neg Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  + Glucose:  + Rhamnose:  neg Xylose:  neg Lactose:  d(neg) Maltose:  + Sucrose:  d Adonitol:  neg Dulcitol:  neg Inositol:  neg Mannitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Citrate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Carbonic anh.:  + β-Galactosidase:  d(neg) ArgDC:  neg γ-Glu transf.:  + LysDC:  neg OrnDC:  neg ProAA:  + AlkalineP:  neg AcidP:  neg Esterase(C4):  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg Pigment:  yellow

    References

    SPECIFIC REFERENCES FOR NEISSERIA ORALIS
  • Bennett2013 - Genome sequence analyses show that Neisseria oralis is the same species as 'Neisseria mucosa var. heidelbergensis'.
  • Wolfgang2013 - Neisseria oralis sp. nov., isolated from healthy gingival plaque and clinical samples.
  • Berger1971 - Neisseria mucosa var. heidelbergensis [Neisseria mucosa var. heidelbergensis].
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NEISSERIA ORALIS
  • PerezBrocal2015 - Metagenomic Analysis of Crohn's Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
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    • Added: December 15, 2021