Neisseria polysaccharea

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Neisseria polysaccharea is a Gram-negative, non-spore-forming, aerobic, non-motile, coccus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 53%. Neisseria polysaccharea is probably a rare gut coloniser. (Riou1987)



  • This organism has been recovered from the pharynx of a healthy person. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Not known to cause human disease.
    • GENERAL CHARACTERISTICS (Riou1987);
    Character Response
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 22℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; maltose;
  • ±
  • Strain-dependent acid from carbs:
  • sucrose;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
  • ✓
  • Nitrite:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Riou1987);
    Class Active Resistant
  • Macrolides:
  • azithromycin; clarithromycin; erythromycin; roxithromycin; telithromycin;
  • Quinolines:
  • ciprofloxacin; levofloxacin; ofloxacin; sparfloxacin;
  • Miscellaneous antibiotics:
  • telithromycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Neisseriales Family:  Neisseriaceae Genus:  Neisseria Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  the pharynx of a healthy person
    DNA G+C(%):  53
    Opt. T:  37℃
    Lower T(℃):  22(neg)
    		Gelatin:  neg DNA:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  neg Glucose:  + Lactose:  neg Maltose:  + Sucrose:  d Mannitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    β-Galactosidase:  neg γ-Glu transf.:  neg Lipase:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    azithromycin:  S(MIC50): 0.06, MIC90: 0.25, RNG: (0.03-0.25)
    erythromycin:  S(MIC50): 1, MIC90: 2, RNG: (0.06-4)
    clarithromycin:  S(MIC50): 0.12, MIC90: 1, RNG: (0.007-1)
    roxithromycin:  S(MIC50): 0.5, MIC90: 2, RNG: (0.06-2)
    telithromycin:  S(MIC50): 0.12, MIC90: 0.25, RNG: (0.007-0.25)
    ciprofloxacin:  S(0.003)
    levofloxacin:  S(0.003)
    ofloxacin:  S(MIC50): 0.007, MIC90: 0.015, RNG: (0.007-0.015)
    sparfloxacin:  S(MIC50): 0.003, MIC90: 0.003, RNG: (0.003-0.007)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)

    References

    SPECIFIC REFERENCES FOR NEISSERIA POLYSACCHAREA
  • Riou1987 - Neisseria polysaccharea sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NEISSERIA POLYSACCHAREA
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: October 10, 2022