Neobacillus jeddahensis

(aka Bacillus jeddahensis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Neobacillus jeddahensis, (aka Bacillus jeddahensis), is a Gram-positive, spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 39.4%. Neobacillus jeddahensis is probably a rare gut coloniser. (Bittar2015)



  • This organism has been recovered from human faeces (Bittar2015). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Bittar2015);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 28℃; grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; L-arabinose; fructose; glucose; mannose; xylose; aesculin; maltose; trehalose; N-Ac glucosamine;
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; glucose; maltose; mannose;
  • Active enzymes:
  • acid phosphatase; esterase C4; esterase lipase C8; β-glucosidase; oxidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Bittar2015);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • NO3➔NO2:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Bittar2015);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem;
  • benzylpenicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Caryophanales Family:  Bacillaceae Genus:  Neobacillus Alt. name:  Bacillus jeddahensis Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (Bittar2015)
    DNA G+C(%):  39.4
    Opt. T:  37℃
    Lower T(℃):  28(+)
    High T(℃):  45(+)
    		Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + L-Arabinose:  + Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  + Melezitose:  w Melibiose:  neg Sucrose:  neg Trehalose:  + Turanose:  neg Amygdalin:  neg Aesculin:  + Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  + Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Glucose:  + Mannose:  + Maltose:  + N_Acetyl_glucosamine:  + Gluconate:  neg Mannitol:  neg Adipate:  neg Citrate:  neg Malate:  neg Phenylacetate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg CystineAA:  neg LeuAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    benzyl-pen:  Res
    imipenem:  Sens
    gentamicin:  Sens
    erythromycin:  Res
    ciprofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    vancomycin:  Res
    rifampicin:  Res
    metronidazole:  Res
    SXT:  Res

    References

    SPECIFIC REFERENCES FOR NEOBACILLUS JEDDAHENSIS
  • Bittar2015 - Non contiguous-finished genome sequence and description of Bacillus jeddahensis sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NEOBACILLUS JEDDAHENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • GENERAL REFERENCES FOR NEOBACILLUS JEDDAHENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
  • Patel2020 - A phylogenomic and comparative genomic framework for resolving the polyphyly of the genus Bacillus: Proposal for six new genera of Bacillus species, Peribacillus gen. nov., Cytobacillus gen. nov., Mesobacillus gen. nov., Neobacillus gen. nov., Metabacillus gen. nov. and Alkalihalobacillus gen. nov.
    • Added: July 12, 2021