Nocardia brevicatena

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Nocardia brevicatena is a Gram-positive, exosporous, aerobic, non-motile, pleiomorph rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Nocardia brevicatena is probably a rare gut coloniser. (Goodfellow2012Bergey; Goodfellow1982)



  • The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Goodfellow2012Bergey); (Goodfellow1982);
    Character Response
  • ±
  • Strain-dependent hydrolysis or digestion:
  • aesculin; hippurate;
  • 🧂
  • Salt tolerance:
  • tolerates 3% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0; tolerates pH 9; Grows optimally at pH 6.3.
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; grows at 40℃; Grows optimally at 36℃.
  • ⥅
  • Substrates assimilated or utilised:
  • adonitol; fructose; galactose; glucose; glycerol; glycogen; inositol; maltose; mannose; melezitose; methyl-α-glucoside; rhamnose; salicin; starch; sucrose; trehalose; acetamide;
  • ±
  • Strain-dependent substrate utilisation:
  • cellubiose; ethanol; serine;
  • Active enzymes:
  • catalase;
    • SPECIAL FEATURES (Goodfellow2012Bergey); (Goodfellow1982);
    Character Response
  • Lysozyme:
  • growth observed (0.005%)
  • ✗
  • Nitrate:
  • not reduced
  • ±
  • Pigments:
  • pink, red, orange
    • RESPONSE TO ANTIBIOTICS (Goodfellow2012Bergey);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Aminoglycosides:
  • kanamycin; neomycin; tobramycin;
  • gentamicin; streptomycin;
  • Polypep/ketides:
  • rifampicin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • lincomycin; novobiocin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinobacteria Order:  Corynebacteriales Family:  Nocardiaceae Genus:  Nocardia Gram stain:  + O2 Relation.:  aerobic Spore:  Exospore Motility:  Sessile Morphology:  Pleiomorph rod Pigment:  pink, red, orange
    Health:  Unknown
    Opt. T:  36℃
    Lower T(℃):  20(+)
    Mid T(℃):  40(+)
    NaCl 3-5%:  3(+)
    Opt. pH:  6.3
    pH 6.0-8.0:  6.0(+)
    pH >8:  9(+)
    		Aesculin:  d Gelatin:  neg Starch:  neg Casein:  neg Chitin:  neg DNA:  neg Hippurate:  d Tween:  20(+) 40(+) 60(+) 80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Xylan:  neg Arbutin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg L-Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Xylose:  neg Cellubiose:  d Lactose:  neg Maltose:  + Melezitose:  + Raffinose:  neg Sucrose:  + Trehalose:  + Adonitol:  + Amygdalin:  neg Erythritol:  neg Ethanol:  d Glycerol:  + Glycogen:  + Inositol:  + Inulin:  neg Mannitol:  neg Me-α-D-Glc:  + Salicin:  + Sorbitol:  neg Starch:  + Ser:  d
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  pink, red, orange
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  R(10U)
    gentamicin:  R(50; disc)
    kanamycin:  S(100; disc)
    neomycin:  S(50; disc)
    streptomycin:  R(100; disc)
    tobramycin:  S(100; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  R(50; disc)
    rifampicin:  R(50; disc)
    lincomycin:  R(100; disc)
    novobiocin:  R(50; disc)

    References

    SPECIFIC REFERENCES FOR NOCARDIA BREVICATENA
  • Goodfellow2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Nocardiaceae, Genus I. Nocardia
  • Goodfellow1982 - Numerical classification of sporoactinomycetes containing meso-diaminopimelic acid in the cell wall.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NOCARDIA BREVICATENA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
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    • Added: May 15, 2022