Nocardia otitidiscaviarum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Nocardia otitidiscaviarum is a Gram-positive, aerobic, non-motile, filamentous bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 66-67%. Nocardia otitidiscaviarum is probably a rare gut coloniser. (Goodfellow2012Bergey)



  • This organism has been recovered from guinea pig ear infection, soil and clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Goodfellow2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; xanthine;
  • 🧂
  • Salt tolerance:
  • tolerates 5% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 45℃;
  • ⥅
  • Substrates assimilated or utilised:
  • arbutin; glucose; inositol; mannitol; alanine; leucine; serine; acetate; pimelate;
  • Active enzymes:
  • catalase; xylosidase; phospholipase C; 2-dTMP;
    • RESPONSE TO ANTIBIOTICS (Goodfellow2012Bergey);
    Class Active Resistant
  • Penicillins:
  • amoxicillin;
  • amoxicillin-clavulanic acid; ampicillin;
  • Tetracyclines:
  • minocycline;
  • Quinolines:
  • pefloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin; kanamycin;
  • Heterocycles:
  • chloramphenicol;
  • trimethoprim; trimethoprim-sulfamethoxazole;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinobacteria Order:  Corynebacteriales Family:  Nocardiaceae Genus:  Nocardia Gram stain:  + O2 Relation.:  aerobic Motility:  Sessile Morphology:  Filamentous
    Health:  Unknown
    Source:  guinea pig ear infection, soil and clinical sources
    DNA G+C(%):  66-67
    Lower T(℃):  30(+)
    High T(℃):  45(+)
    NaCl 3-5%:  5(+)
    		Aesculin:  + Casein:  neg Tyrosine:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Galactose:  neg Glucose:  + Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Raffinose:  neg Sucrose:  neg Trehalose:  w Adonitol:  neg Arbutin:  + Erythritol:  neg Gluconate:  w Inositol:  + Mannitol:  + Sorbitol:  neg Ala:  + Leu:  + Pro:  neg Ser:  + Val:  neg Acetate:  + Adipate:  neg Citrate:  neg 3-Hydroxybenzoate:  neg 4-Hydroxybenzoate:  neg Pimelate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Xylosidase:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(10; disc)
    Augmentin:  Res
    ampicillin:  Res
    amikacin:  Sens
    gentamicin:  Sens
    kanamycin:  Sens
    pefloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  Sens
    chloramphenicol:  Sens
    trimethoprim:  Res
    SXT:  Res
    clindamycin:  Sens

    References

    SPECIFIC REFERENCES FOR NOCARDIA OTITIDISCAVIARUM
  • Goodfellow2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Nocardiaceae, Genus I. Nocardia
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NOCARDIA OTITIDISCAVIARUM
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
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    • Added: May 15, 2022