Nocardioides massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Nocardioides massiliensis is a Gram-positive, non-spore-forming, strictly aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 71.0%. Nocardioides massiliensis is likely to be transient and not a long-term gut coloniser. (Dubourg2016)



  • This organism has been recovered from human faeces (Dubourg2016). Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe; unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Dubourg2016);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 37℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • lactose;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; Arg arylamidase; catalase; esterase C4; esterase lipase C8; α-glucosidase; β-glucosidase; Leu arylamidase; Pro arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Dubourg2016);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Dubourg2016);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem; penicillin G;
  • Macrolides:
  • erythromycin;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;
  • metronidazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Propionibacteriales Family:  Nocardioidaceae Genus:  Nocardioides Gram stain:  + O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (Dubourg2016)
    DNA G+C(%):  71.0
    Opt. T:  37℃
    Lower T(℃):  25(+)
    Mid T(℃):  37(+)
    High T(℃):  45(neg)
    		Aesculin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  + Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Amygdalin:  neg Aesculin:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg ArgAA:  + CystineAA:  neg HisAA:  neg LeuAA:  + ProAA:  + PheAA:  neg SerAA:  neg TyrAA:  neg ValAA:  neg AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    penicillin_G:  Sens
    imipenem:  Sens
    gentamicin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens
    rifampicin:  Sens
    metronidazole:  Res
    SXT:  Sens

    References

    SPECIFIC REFERENCES FOR NOCARDIOIDES MASSILIENSIS
  • Dubourg2016 - Noncontiguous finished genome sequence and description of Nocardioides massiliensis sp. nov. GD13T.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NOCARDIOIDES MASSILIENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: July 12, 2021