Novosphingobium capsulatum

(aka Flavobacterium capsulatum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Novosphingobium capsulatum, (aka Flavobacterium capsulatum), is a Gram-negative, non-spore-forming, strictly aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 63.1%. Novosphingobium capsulatum is likely to be transient and not a long-term gut coloniser. (Yabuuchi1990; Takeuchi2001; Yabuuchi2002; Leifson1962)



  • This organism has been recovered from human faeces and distilled water. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe; unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Yabuuchi1990); (Takeuchi2001); (Yabuuchi2002); (Leifson1962);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; DNA; starch;
  • 🧂
  • Salt tolerance:
  • tolerates 3% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 40℃;
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; L-arabinose; fructose; galactose; glucose; mannose; rhamnose; xylose; lactose; maltose; melezitose; melibiose; raffinose; sucrose; trehalose; glycerol;
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; amygdalin; L-arabinose; arbutin; cellubiose; aesculin; fructose; fucose; galactose; gluconate; gentiobiose; glucose; glycerol; lactose; maltose; mannose; rhamnose; raffinose; salicin; starch; xylose; glutamate; L-malate; succinate; glutamine;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; catalase; cystine arylamidase; DNase; esterase lipase C8; β-galactosidase; α-glucosidase; β-glucosidase; Leu arylamidase; lipase C14; oxidase; phosphoamidase; phenylalanine deaminase; Val arylamidase;
    • SPECIAL FEATURES (Yabuuchi1990); (Yabuuchi2002);
    Character Response
  • ✓
  • Metabolites produced:
  • H₂S;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrite:
  • not reduced
  • ✗
  • NO3➔NO2:
  • not reduced
  • Pigments:
  • yellow
    • RESPONSE TO ANTIBIOTICS (Yabuuchi1990); (Yabuuchi2002);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; ampicillin; carbenicillin; imipenem; meropenem; penicillin G; ticarcillin;
  • aztreonam;
  • Cephalosporins:
  • cefaclor; cefazolin; cefmetazole; cefotaxime; ceftazidime; ceftizoxime; cephalothin;
  • Macrolides:
  • clarithromycin;
  • roxithromycin;
  • Tetracyclines:
  • doxycycline; minocycline; tetracycline;
  • Quinolines:
  • levofloxacin;
  • ciprofloxacin; nalidixic-acid; norfloxacin; ofloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin; netilmycin; tobramycin;
  • streptomycin;
  • Heterocycles:
  • chloramphenicol; trimethoprim-sulfamethoxazole;
  • trimethoprim;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Alphaproteobacteria Order:  Sphingomonadales Family:  Sphingomonadaceae Genus:  Novosphingobium Alt. name:  Flavobacterium capsulatum Gram stain:  neg O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  yellow
    Health:  Unknown
    Source:  human faeces and distilled water
    DNA G+C(%):  63.1
    Mid T(℃):  40(neg)
    NaCl 3-5%:  3(+)
    		Aesculin:  + Urea:  neg Gelatin:  neg Starch:  + DNA:  + Tween:  80(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + L-Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Ribose:  neg Xylose:  + Lactose:  + Maltose:  + Melezitose:  + Melibiose:  + Sucrose:  + Trehalose:  + Inulin:  neg Adonitol:  neg Dulcitol:  neg Glycerol:  + Inositol:  neg Mannitol:  neg Sorbitol:  neg Ethanol:  + Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  + D-Fucose:  neg Galactose:  + Glucose:  + D-Lyxose:  neg Mannose:  + Rhamnose:  + Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  + Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melibiose:  neg Raffinose:  + D-Turanose:  neg N_Acetyl_glucosamine:  + Adonitol:  neg Amygdalin:  + D-Arabitol:  neg L-Arabitol:  neg Arbutin:  + Dulcitol:  neg Erythritol:  neg Aesculin:  + Gluconate:  + Glucosamine:  neg Glycerol:  + Glycogen:  neg Inulin:  neg Mannitol:  neg Me-α-D-Glc:  neg Salicin:  + Sorbitol:  neg Starch:  + Xylitol:  neg Ala:  neg Betaine:  neg Glu:  + Histamine:  neg His:  neg Trigonelline:  neg Trp:  neg Adipate:  neg Benzoate:  neg Caprate:  neg Citrate:  neg Glutarate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg L-Malate:  + Malonate:  neg Phenylacetate:  neg Phenylpropionate:  neg Succinate:  + D-Tartrate:  neg L-Tartrate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg LysDC:  neg OrnDC:  neg Phe deaminase:  + Trypsin:  neg CystineAA:  + LeuAA:  + ValAA:  + AlkalineP:  + AcidP:  + DNAse:  + EstLip(C8):  + Lipase(C14):  + Phosphoamidase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  + Indole:  neg Pigment:  yellow
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(25; disc)
    Augmentin:  S(30; disc)
    ampicillin:  S(10; disc)
    aztreonam:  R(30; disc)
    carbenicil:  Sens
    penicillin_G:  S(10U)
    piperacillin:  Var(MIC50): 100; disc), MIC90: Var(100; disc
    ticarcillin:  Sens
    imipenem:  S(10; disc)
    meropenem:  S(10; disc)
    cefaclor:  S(30; disc)
    cefazolin:  S(30; disc)
    cefmetazole:  S(30; disc)
    cefoperazone:  Var(MIC50): 75; disc), MIC90: Var(75; disc
    cefotaxime:  Sens
    ceftazidime:  S(30; disc)
    ceftizoxime:  Sens
    cephalothin:  Sens
    moxalactam:  Var(MIC50): 30; disc), MIC90: Var(30; disc
    amikacin:  S(30; disc)
    gentamicin:  S(10; disc)
    netilmycin:  Sens
    streptomycin:  Res
    tobramycin:  Sens
    erythromycin:  Var(MIC50): 15; disc), MIC90: Var(15; disc
    clarithromycin:  S(15; disc)
    roxithromycin:  R(15; disc)
    ciprofloxacin:  R(5; disc)
    levofloxacin:  S(5; disc)
    nalidixic-acid:  Res
    norfloxacin:  R(10; disc)
    ofloxacin:  R(5; disc)
    sparfloxacin:  Var(MIC50): 5; disc), MIC90: Var(5; disc
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(10; disc)
    minocycline:  S(30; disc)
    tetracycline:  S(30; disc)
    chloramphenicol:  Sens
    trimethoprim:  R(5; disc)
    SXT:  S(25; disc)
    polymyxin_B:  Var(MIC50): 300; disc), MIC90: Var(300; disc

    References

    SPECIFIC REFERENCES FOR NOVOSPHINGOBIUM CAPSULATUM
  • Yabuuchi1990 - Proposals of Sphingomonas paucimobilis gen. nov. and comb. nov., Sphingomonas parapaucimobilis sp. nov., Sphingomonas yanoikuyae sp. nov., Sphingomonas adhaesiva sp. nov., Sphingomonas capsulata comb, nov., and Two Genospecies of the Genus Sphingomonas.
  • Takeuchi2001 - Proposal of the genus Sphingomonas sensu stricto and three new genera, Sphingobium, Novosphingobium and Sphingopyxis, on the basis of phylogenetic and chemotaxonomic analyses.
  • Yabuuchi2002 - Emendation of the genus Sphingomonas Yabuuchi et al. 1990 and junior objective synonymy of the species of three genera, Sphingobium, Novosphingobium and Sphingopyxis, in conjunction with Blastomonas ursincola.
  • Leifson1962 - The Bacterial Flora of Distilled and Stored Water. III. new species of the genera Corynebacterium, Flavobacterium, Spirillum and Pseudomonas
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NOVOSPHINGOBIUM CAPSULATUM
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • ...............................
    • Added: December 15, 2021