Numidum massiliense

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Numidum massiliense is a Gram-positive, spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 52.1%. Numidum massiliense is probably a rare gut coloniser. (Alou2016d)



  • This organism has been recovered from human faeces (Alou2016d). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Alou2016d);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 56℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; ribose; lactose; maltose; mannitol;
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; amygdalin; aesculin; fructose; galactose; glucose; lactose; maltose; mannitol; mannose; ribose; D-tagatose; trehalose; xylose; adipate;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; catalase; chymotrypsin; esterase C4; esterase lipase C8; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase; Leu arylamidase; trypsin;
    • SPECIAL FEATURES (Alou2016d);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • NO3➔NO2:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Alou2016d);
    Class Active Resistant
  • Penicillins:
  • imipenem; ticarcillin-clavulanic acid;
  • penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin-500;
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • nitrofurantoin; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • teicoplanin;
  • Miscellaneous antibiotics:
  • colistin; polymyxin B;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Bacillaceae Genus:  Numidum Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (Alou2016d)
    DNA G+C(%):  52.1
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  56(+)
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Ribose:  + Lactose:  + Maltose:  + Sucrose:  neg Mannitol:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Fructose:  + Galactose:  + Glucose:  + Mannose:  + Ribose:  + D-Tagatose:  + Xylose:  + Lactose:  + Maltose:  + Trehalose:  + N_Acetyl_glucosamine:  + Amygdalin:  + Aesculin:  + Mannitol:  + Adipate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg Ac-β-glcamnd:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + Chymotrypsin:  + Trypsin:  + LeuAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  Res
    tica-clav:  Sens
    imipenem:  Sens
    gentamicin:  R(15; disc)
    gentamicin-500:  Sens
    erythromycin:  Res
    ciprofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    teicoplanin:  Sens
    rifampicin:  Sens
    metronidazole:  Sens
    nitrofurantoin:  Res
    SXT:  Res
    colistin:  Res
    polymyxin_B:  Res

    References

    SPECIFIC REFERENCES FOR NUMIDUM MASSILIENSE
  • Alou2016d - Numidum massiliense gen. nov., sp. nov., a new member of the Bacillaceae family isolated from the human gut.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR NUMIDUM MASSILIENSE
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • GENERAL REFERENCES FOR NUMIDUM MASSILIENSE
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: July 12, 2021